COMP <GO>
SPRO vs GOSS // FORWARD P/E MULTIPLE
Spero Therapeutics Inc. (NASDAQ) VS. Gossamer Bio Inc. (NASDAQ) • 15-METRIC TALLY: SPRO 5
— GOSS 2
■ METRIC PARITY
LAST: $1.06 (-4.50%) • MKT CAP: $64.6M
forward-pe
6.3x
LAST: $10.38 (-2.90%) • MKT CAP: $65.4M
forward-pe
—
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (SPRO VS. GOSS)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | SPRO | GOSS | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | — | — | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | 26.60% | -35.00% | +61.60 | SPRO | /roic <GO> |
| EV/EBITDA & P/E Valuation | 5.1x | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | -19.53% | — | — | TIE | /fcf-yield <GO> |
| Operating Margin | 50.20% | -60.00% | +110.20 | SPRO | /operating-margins <GO> |
| Net Profit Margin | 68.00% | -60.00% | +128.00 | SPRO | /net-margins <GO> |
| Revenue Growth (YoY) | 180.00% | -57.70% | +237.70 | SPRO | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 0.20 | — | — | TIE | /balance-sheet <GO> |
| Piotroski F-Score Quality | 5/9 | 1/9 | +4.00 | SPRO | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 41.2 | 51.3 | -10.13 | GOSS | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | — | — | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple ACTIVE | 6.3x | — | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $64.6M | $65.4M | -$743.6K | GOSS | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | SPRO REV | GOSS REV | SPRO GROSS % | GOSS GROSS % | SPRO FCF | GOSS FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $12.6M | $48.5M | — | — | -$12.6M | -$171.3M |
| FY 2024 | $371.0K | $114.7M | — | — | -$23.4M | -$3.5M |
| FY 2023 | $933.0K | $0 | — | — | -$33.0M | -$159.2M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
SPRO // BETA —
GOSS // BETA —