COMP <GO>
SLN vs OPK // 10Y YIELD & FRED MACRO BETA
Silence Therapeutics Plc American Depository Share (NASDAQ) VS. OPKO Health Inc. (NASDAQ) • 15-METRIC TALLY: SLN 4
— OPK 5
■ METRIC PARITY
LAST: $19.80 (+0.46%) • MKT CAP: $1.23B
macro-sensitivity
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LAST: $1.66 (+2.47%) • MKT CAP: $1.24B
macro-sensitivity
—
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (SLN VS. OPK)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | SLN | OPK | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | 61.50% | 33.90% | +27.60 | SLN | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -35.00% | -10.20% | -24.80 | OPK | /roic <GO> |
| EV/EBITDA & P/E Valuation | — | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | -5.06% | -14.41% | +9.35 | SLN | /fcf-yield <GO> |
| Operating Margin | -60.00% | -19.30% | -40.70 | OPK | /operating-margins <GO> |
| Net Profit Margin | -60.00% | -60.00% | 0.00 | TIE | /net-margins <GO> |
| Revenue Growth (YoY) | -65.00% | -14.90% | -50.10 | OPK | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 3.36 | 0.20 | +3.16 | SLN | /balance-sheet <GO> |
| Piotroski F-Score Quality | 3/9 | 4/9 | -1.00 | OPK | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 78.9 | 58.9 | +20.05 | SLN | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta ACTIVE | — | — | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple | — | — | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $1.23B | $1.24B | -$8.3M | OPK | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | SLN REV | OPK REV | SLN GROSS % | OPK GROSS % | SLN FCF | OPK FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $559.0K | $606.9M | 61.5% | 33.9% | -$62.3M | -$178.5M |
| FY 2024 | $43.3M | $713.1M | 72.7% | 30.6% | -$67.9M | -$183.5M |
| FY 2023 | $31.6M | $863.5M | — | — | -$49.5M | -$28.2M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
SLN // BETA —
OPK // BETA —