COMP <GO>
SION vs TRDA // OPERATING MARGIN
Sionna Therapeutics Inc. (NASDAQ) VS. Entrada Therapeutics Inc. (NASDAQ) • 15-METRIC TALLY: SION 1
— TRDA 2
■ METRIC PARITY
LAST: $3.73 (-3.62%) • MKT CAP: $168.6M
operating-margins
—
LAST: $5.11 (+12.68%) • MKT CAP: $199.0M
operating-margins
-60.00%
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (SION VS. TRDA)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | SION | TRDA | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | — | — | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -28.30% | -35.00% | +6.70 | SION | /roic <GO> |
| EV/EBITDA & P/E Valuation | — | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | — | — | — | TIE | /fcf-yield <GO> |
| Operating Margin ACTIVE | — | -60.00% | — | TIE | /operating-margins <GO> |
| Net Profit Margin | — | -60.00% | — | TIE | /net-margins <GO> |
| Revenue Growth (YoY) | — | -65.00% | — | TIE | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | — | 0.20 | — | TIE | /balance-sheet <GO> |
| Piotroski F-Score Quality | 2/9 | 2/9 | 0.00 | TIE | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 32.0 | 49.6 | -17.60 | TRDA | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | — | — | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple | — | — | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $168.6M | $199.0M | -$30.3M | TRDA | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | SION REV | TRDA REV | SION GROSS % | TRDA GROSS % | SION FCF | TRDA FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $249.1M | $25.4M | — | — | -$66.7M | -$129.6M |
| FY 2024 | $197.6M | $210.8M | — | — | -$52.8M | -$44.7M |
| FY 2023 | — | $129.0M | — | — | — | $139.8M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
SION // BETA —
TRDA // BETA —