COMP <GO>
SEPN vs ABBV // EV/EBITDA & P/E VALUATION
Septerna Inc. (NASDAQ) VS. AbbVie Inc. (NYSE) • 15-METRIC TALLY: SEPN 4
— ABBV 6
■ METRIC PARITY
LAST: $45.23 (+2.22%) • MKT CAP: $2.11B
valuation
—
LAST: $290.79 (+1.68%) • MKT CAP: $513.86B
valuation
33.3x
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (SEPN VS. ABBV)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | SEPN | ABBV | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | — | 70.20% | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -20.70% | 29.00% | -49.70 | ABBV | /roic <GO> |
| EV/EBITDA & P/E Valuation ACTIVE | — | 33.3x | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | 5.19% | 3.47% | +1.72 | SEPN | /fcf-yield <GO> |
| Operating Margin | -60.00% | 24.60% | -84.60 | ABBV | /operating-margins <GO> |
| Net Profit Margin | -60.00% | 6.90% | -66.90 | ABBV | /net-margins <GO> |
| Revenue Growth (YoY) | 180.00% | 8.60% | +171.40 | SEPN | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 2.27% | -2.27 | ABBV | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 5.87 | 5.33 | +0.54 | SEPN | /balance-sheet <GO> |
| Piotroski F-Score Quality | 6/9 | 7/9 | -1.00 | ABBV | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 65.2 | 65.1 | +0.06 | SEPN | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | — | 1.15 | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple | — | 113.1x | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $2.11B | $513.86B | -$511.75B | ABBV | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | SEPN REV | ABBV REV | SEPN GROSS % | ABBV GROSS % | SEPN FCF | ABBV FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $46.0M | $61.16B | — | 70.2% | $109.7M | $17.82B |
| FY 2024 | $1.1M | $56.33B | — | 70.0% | -$69.6M | $17.83B |
| FY 2023 | $151.0K | $54.32B | — | — | -$38.7M | $20.39B |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
SEPN // BETA —
ABBV // BETA 1.15