COMP <GO>
SDGR vs SEPN // EV/EBITDA & P/E VALUATION
Schrodinger Inc. (NASDAQ) VS. Septerna Inc. (NASDAQ) • 15-METRIC TALLY: SDGR 2
— SEPN 6
■ METRIC PARITY
LAST: $26.19 (-3.50%) • MKT CAP: $2.03B
valuation
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LAST: $43.20 (-1.82%) • MKT CAP: $2.05B
valuation
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15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (SDGR VS. SEPN)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | SDGR | SEPN | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | 55.70% | — | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -35.00% | -20.70% | -14.30 | SEPN | /roic <GO> |
| EV/EBITDA & P/E Valuation ACTIVE | — | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | 0.56% | 5.19% | -4.63 | SEPN | /fcf-yield <GO> |
| Operating Margin | -60.00% | -60.00% | 0.00 | TIE | /operating-margins <GO> |
| Net Profit Margin | -40.40% | -60.00% | +19.60 | SDGR | /net-margins <GO> |
| Revenue Growth (YoY) | 23.30% | 180.00% | -156.70 | SEPN | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 2.64 | 5.87 | -3.23 | SEPN | /balance-sheet <GO> |
| Piotroski F-Score Quality | 7/9 | 6/9 | +1.00 | SDGR | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 51.8 | 62.4 | -10.60 | SEPN | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | — | — | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple | — | — | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $2.03B | $2.05B | -$23.6M | SEPN | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | SDGR REV | SEPN REV | SDGR GROSS % | SEPN GROSS % | SDGR FCF | SEPN FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $255.9M | $46.0M | 55.7% | — | $12.5M | $109.7M |
| FY 2024 | $207.5M | $1.1M | 63.6% | — | -$164.7M | -$69.6M |
| FY 2023 | $216.7M | $151.0K | — | — | -$136.7M | -$38.7M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
SDGR // BETA —
SEPN // BETA —