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RARE vs GPCR // ENTERPRISE SCALE & MARKET CAP

Ultragenyx Pharmaceutical Inc. (NASDAQ) VS. Structure Therapeutics Inc. (NASDAQ) • 15-METRIC TALLY: RARE 3 — GPCR 1
▲ ENTERPRISE SCALE & MARKET CAP LEADER: RARE
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (RARE VS. GPCR) EMERALD CELL = QUANTITATIVE EDGE
INSTITUTIONAL METRIC RARE GPCR SPREAD (A - B) ADVANTAGE DEDICATED URL
Gross Profit Margin — — — TIE /gross-margins <GO>
Return on Invested Capital (ROIC) -35.00% -19.50% -15.50 GPCR /roic <GO>
EV/EBITDA & P/E Valuation — — — TIE /valuation <GO>
Free Cash Flow Yield — -14.43% — TIE /fcf-yield <GO>
Operating Margin -60.00% — — TIE /operating-margins <GO>
Net Profit Margin -60.00% — — TIE /net-margins <GO>
Revenue Growth (YoY) 20.20% — — TIE /revenue-growth <GO>
Dividend Yield & FCF Payout Safety 0.00% 0.00% 0.00 TIE /dividend-safety <GO>
Altman Z-Score & Debt/Equity 0.20 — — TIE /balance-sheet <GO>
Piotroski F-Score Quality 3/9 1/9 +2.00 RARE /piotroski-score <GO>
Options Implied Move & Put/Call Skew — — — TIE /options-implied-move <GO>
RSI-14 & 200D SMA Momentum 49.5 26.9 +22.60 RARE /rsi-technicals <GO>
10Y Yield & FRED Macro Beta — — — TIE /macro-sensitivity <GO>
Forward P/E Multiple — — — TIE /forward-pe <GO>
Enterprise Scale & Market Cap ACTIVE $1.59B $1.56B $27.7M RARE /market-cap <GO>
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
FISCAL YEAR RARE REV GPCR REV RARE GROSS % GPCR GROSS % RARE FCF GPCR FCF
FY 2025 $673.0M $494.4M — — -$472.0M -$225.8M
FY 2024 $560.0M $443.0M — — -$421.0M -$117.9M
FY 2023 $434.0M $287.8M — — -$475.0M -$79.5M
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
RARE // BETA —
GPCR // BETA —