COMP <GO>
GYRE vs WVE // GROSS PROFIT MARGIN
Gyre Therapeutics Inc. (NASDAQ) VS. Wave Life Sciences Inc. (NASDAQ) • 15-METRIC TALLY: GYRE 6
— WVE 2
■ METRIC PARITY
LAST: $6.41 (-9.59%) • MKT CAP: $714.8M
gross-margins
95.40%
LAST: $3.63 (-0.28%) • MKT CAP: $715.9M
gross-margins
—
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (GYRE VS. WVE)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | GYRE | WVE | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin ACTIVE | 95.40% | — | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | 25.40% | -35.00% | +60.40 | GYRE | /roic <GO> |
| EV/EBITDA & P/E Valuation | 53.3x | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | -0.03% | — | — | TIE | /fcf-yield <GO> |
| Operating Margin | 9.90% | -60.00% | +69.90 | GYRE | /operating-margins <GO> |
| Net Profit Margin | 8.50% | -60.00% | +68.50 | GYRE | /net-margins <GO> |
| Revenue Growth (YoY) | 10.20% | -60.50% | +70.70 | GYRE | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 14.33 | 0.85 | +13.48 | GYRE | /balance-sheet <GO> |
| Piotroski F-Score Quality | 5/9 | 2/9 | +3.00 | GYRE | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 49.8 | 50.6 | -0.80 | WVE | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | — | — | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple | 67.2x | — | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $714.8M | $715.9M | -$1.2M | WVE | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | GYRE REV | WVE REV | GYRE GROSS % | WVE GROSS % | GYRE FCF | WVE FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $116.6M | $42.7M | 95.4% | — | -$180.0K | -$188.2M |
| FY 2024 | $105.8M | $108.3M | 96.3% | — | -$6.0M | -$152.0M |
| FY 2023 | $113.5M | $113.3M | — | — | $25.9M | -$19.4M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
GYRE // BETA —
WVE // BETA —