COMP <GO>
ANVS vs HOWL // NET PROFIT MARGIN
Annovis Bio Inc. (NYSE) VS. Werewolf Therapeutics Inc. (NASDAQ) • 15-METRIC TALLY: ANVS 2
— HOWL 1
■ METRIC PARITY
LAST: $1.08 (-4.42%) • MKT CAP: $48.2M
net-margins
—
LAST: $1.05 (+6.48%) • MKT CAP: $47.9M
net-margins
—
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (ANVS VS. HOWL)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | ANVS | HOWL | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | — | — | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -35.00% | -35.00% | 0.00 | TIE | /roic <GO> |
| EV/EBITDA & P/E Valuation | — | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | — | — | — | TIE | /fcf-yield <GO> |
| Operating Margin | — | — | — | TIE | /operating-margins <GO> |
| Net Profit Margin ACTIVE | — | — | — | TIE | /net-margins <GO> |
| Revenue Growth (YoY) | — | — | — | TIE | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | — | — | — | TIE | /balance-sheet <GO> |
| Piotroski F-Score Quality | 1/9 | 3/9 | -2.00 | HOWL | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 51.7 | 51.2 | +0.50 | ANVS | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | — | — | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple | — | — | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $48.2M | $47.9M | $303.8K | ANVS | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | ANVS REV | HOWL REV | ANVS GROSS % | HOWL GROSS % | ANVS FCF | HOWL FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $83.1M | $169.9M | — | — | -$25.6M | -$60.3M |
| FY 2024 | $74.7M | $206.1M | — | — | -$21.9M | -$56.4M |
| FY 2023 | $126.1M | $113.4M | — | — | -$40.0M | -$32.6M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
ANVS // BETA —
HOWL // BETA —