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ANAB vs TYRA // GROSS PROFIT MARGIN

AnaptysBio Inc. (NASDAQ) VS. Tyra Biosciences Inc. (NASDAQ) • 15-METRIC TALLY: ANAB 3 — TYRA 2
■ METRIC PARITY
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (ANAB VS. TYRA) EMERALD CELL = QUANTITATIVE EDGE
INSTITUTIONAL METRIC ANAB TYRA SPREAD (A - B) ADVANTAGE DEDICATED URL
Gross Profit Margin ACTIVE — — — TIE /gross-margins <GO>
Return on Invested Capital (ROIC) 85.00% -35.00% +120.00 ANAB /roic <GO>
EV/EBITDA & P/E Valuation 5.7x — — TIE /valuation <GO>
Free Cash Flow Yield 1.36% -6.45% +7.81 ANAB /fcf-yield <GO>
Operating Margin 75.00% — — TIE /operating-margins <GO>
Net Profit Margin -5.60% — — TIE /net-margins <GO>
Revenue Growth (YoY) 157.00% — — TIE /revenue-growth <GO>
Dividend Yield & FCF Payout Safety 0.00% 0.00% 0.00 TIE /dividend-safety <GO>
Altman Z-Score & Debt/Equity — — — TIE /balance-sheet <GO>
Piotroski F-Score Quality 7/9 2/9 +5.00 ANAB /piotroski-score <GO>
Options Implied Move & Put/Call Skew — — — TIE /options-implied-move <GO>
RSI-14 & 200D SMA Momentum 48.0 51.8 -3.80 TYRA /rsi-technicals <GO>
10Y Yield & FRED Macro Beta — — — TIE /macro-sensitivity <GO>
Forward P/E Multiple — — — TIE /forward-pe <GO>
Enterprise Scale & Market Cap $1.44B $1.48B -$36.7M TYRA /market-cap <GO>
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
FISCAL YEAR ANAB REV TYRA REV ANAB GROSS % TYRA GROSS % ANAB FCF TYRA FCF
FY 2025 $234.6M $0 — — $19.6M -$95.3M
FY 2024 $91.3M $0 — — -$135.7M -$70.4M
FY 2023 $17.2M $0 — — -$120.8M -$50.1M
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
ANAB // BETA —
TYRA // BETA —