COMP <GO>
XENE vs AMLX // EV/EBITDA & P/E VALUATION
Xenon Pharmaceuticals Inc. (NASDAQ) VS. Amylyx Pharmaceuticals Inc. (NASDAQ) • 15-METRIC TALLY: XENE 2
— AMLX 2
■ METRIC PARITY
LAST: $37.54 (+3.30%) • MKT CAP: $3.64B
valuation
—
LAST: $28.68 (+2.17%) • MKT CAP: $3.60B
valuation
—
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (XENE VS. AMLX)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | XENE | AMLX | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | — | — | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -35.00% | -35.00% | 0.00 | TIE | /roic <GO> |
| EV/EBITDA & P/E Valuation ACTIVE | — | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | -7.70% | -3.43% | -4.27 | AMLX | /fcf-yield <GO> |
| Operating Margin | -36.70% | — | — | TIE | /operating-margins <GO> |
| Net Profit Margin | -34.00% | — | — | TIE | /net-margins <GO> |
| Revenue Growth (YoY) | 7.70% | — | — | TIE | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 26.00 | — | — | TIE | /balance-sheet <GO> |
| Piotroski F-Score Quality | 5/9 | 3/9 | +2.00 | XENE | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 44.9 | 51.9 | -6.99 | AMLX | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | 1.10 | — | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple | 29.0x | — | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $3.64B | $3.60B | $37.2M | XENE | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | XENE REV | AMLX REV | XENE GROSS % | AMLX GROSS % | XENE FCF | AMLX FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $0 | $0 | — | — | -$279.9M | -$123.5M |
| FY 2024 | $0 | $87.4M | — | 93.2% | -$184.5M | -$167.8M |
| FY 2023 | $0 | $380.8M | — | — | -$151.1M | $11.9M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
XENE // BETA 1.10
AMLX // BETA —