COMP <GO>

SION vs WHWK // EV/EBITDA & P/E VALUATION

Sionna Therapeutics Inc. (NASDAQ) VS. Whitehawk Therapeutics Inc. (NASDAQ) • 15-METRIC TALLY: SION 1 — WHWK 3

■ METRIC PARITY

LAST: $3.87 (-3.25%) • MKT CAP: $180.8M

valuation

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LAST: $3.24 (-1.82%) • MKT CAP: $188.1M

valuation

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15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (SION VS. WHWK) EMERALD CELL = QUANTITATIVE EDGE

INSTITUTIONAL METRIC	SION	WHWK	SPREAD (A - B)	ADVANTAGE	DEDICATED URL
Gross Profit Margin	—	89.40%	—	TIE	/gross-margins <GO>
Return on Invested Capital (ROIC)	-28.30%	-35.00%	+6.70	SION	/roic <GO>
EV/EBITDA & P/E Valuation ACTIVE	—	—	—	TIE	/valuation <GO>
Free Cash Flow Yield	—	—	—	TIE	/fcf-yield <GO>
Operating Margin	—	-60.00%	—	TIE	/operating-margins <GO>
Net Profit Margin	—	-60.00%	—	TIE	/net-margins <GO>
Revenue Growth (YoY)	—	-65.00%	—	TIE	/revenue-growth <GO>
Dividend Yield & FCF Payout Safety	0.00%	0.00%	0.00	TIE	/dividend-safety <GO>
Altman Z-Score & Debt/Equity	—	3.11	—	TIE	/balance-sheet <GO>
Piotroski F-Score Quality	2/9	3/9	-1.00	WHWK	/piotroski-score <GO>
Options Implied Move & Put/Call Skew	—	—	—	TIE	/options-implied-move <GO>
RSI-14 & 200D SMA Momentum	29.4	42.9	-13.40	WHWK	/rsi-technicals <GO>
10Y Yield & FRED Macro Beta	—	—	—	TIE	/macro-sensitivity <GO>
Forward P/E Multiple	—	—	—	TIE	/forward-pe <GO>
Enterprise Scale & Market Cap	$180.8M	$188.1M	-$7.3M	WHWK	/market-cap <GO>

5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY

FISCAL YEAR	SION REV	WHWK REV	SION GROSS %	WHWK GROSS %	SION FCF	WHWK FCF
FY 2025	$0	$7.1M	—	89.4%	-$66.7M	-$98.0M
FY 2024	$0	$26.0M	—	88.4%	-$52.8M	-$61.2M
FY 2023	—	$24.4M	—	—	—	-$59.7M

FRED MACRO REGIME CORRELATION COMPARISON PEARSON r

SION // BETA —

WHWK // BETA —