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IONS vs UNH // FREE CASH FLOW YIELD

Ionis Pharmaceuticals Inc. (NASDAQ) VS. UnitedHealth Group Incorporated (NYSE) • 15-METRIC TALLY: IONS 3 — UNH 11
▲ FREE CASH FLOW YIELD LEADER: UNH
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (IONS VS. UNH) EMERALD CELL = QUANTITATIVE EDGE
INSTITUTIONAL METRIC IONS UNH SPREAD (A - B) ADVANTAGE DEDICATED URL
Gross Profit Margin 96.00% 88.57% +7.43 IONS /gross-margins <GO>
Return on Invested Capital (ROIC) -20.90% 11.47% -32.37 UNH /roic <GO>
EV/EBITDA & P/E Valuation — 16.4x — TIE /valuation <GO>
Free Cash Flow Yield ACTIVE -4.34% 6.48% -10.82 UNH /fcf-yield <GO>
Operating Margin -40.40% 4.82% -45.22 UNH /operating-margins <GO>
Net Profit Margin -40.40% 3.14% -43.54 UNH /net-margins <GO>
Revenue Growth (YoY) 33.80% 6.46% +27.34 IONS /revenue-growth <GO>
Dividend Yield & FCF Payout Safety 0.00% 2.28% -2.28 UNH /dividend-safety <GO>
Altman Z-Score & Debt/Equity 1.08 3.12 -2.04 UNH /balance-sheet <GO>
Piotroski F-Score Quality 5/9 7/9 -2.00 UNH /piotroski-score <GO>
Options Implied Move & Put/Call Skew 7.20% 6.74% +0.46 UNH /options-implied-move <GO>
RSI-14 & 200D SMA Momentum 43.1 56.0 -12.91 UNH /rsi-technicals <GO>
10Y Yield & FRED Macro Beta 1.09 0.33 +0.76 IONS /macro-sensitivity <GO>
Forward P/E Multiple 22.0x 17.1x +4.91 UNH /forward-pe <GO>
Enterprise Scale & Market Cap $7.38B $364.66B -$357.28B UNH /market-cap <GO>
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
FISCAL YEAR IONS REV UNH REV IONS GROSS % UNH GROSS % IONS FCF UNH FCF
FY 2025 $943.7M $447.57B 98.3% 88.7% -$320.0M $16.07B
FY 2024 $705.1M $400.28B 98.4% 88.3% -$546.2M $20.70B
FY 2023 $787.6M $371.62B 44.0% 89.6% -$343.0M $25.68B
FY 2022 — $324.16B — 89.6% — $23.40B
FY 2021 — $287.60B — 89.2% — $19.89B
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
IONS // BETA 1.09
UNH // BETA 0.33