COMP <GO>
SYRE vs ABBV // GROSS PROFIT MARGIN
Spyre Therapeutics Inc. (NASDAQ) VS. AbbVie Inc. (NYSE) • 15-METRIC TALLY: SYRE 5
— ABBV 9
▲ GROSS PROFIT MARGIN LEADER: ABBV
LAST: $96.56 (-2.43%) • MKT CAP: $10.33B
gross-margins
44.00%
LAST: $294.89 (+1.41%) • MKT CAP: $513.86B
gross-margins
70.20%
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (SYRE VS. ABBV)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | SYRE | ABBV | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin ACTIVE | 44.00% | 70.20% | -26.20 | ABBV | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -20.00% | 29.00% | -49.00 | ABBV | /roic <GO> |
| EV/EBITDA & P/E Valuation | — | 33.3x | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | -1.64% | 3.47% | -5.11 | ABBV | /fcf-yield <GO> |
| Operating Margin | 16.50% | 24.60% | -8.10 | ABBV | /operating-margins <GO> |
| Net Profit Margin | 12.40% | 6.90% | +5.50 | SYRE | /net-margins <GO> |
| Revenue Growth (YoY) | 17.60% | 8.60% | +9.00 | SYRE | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 2.27% | -2.27 | ABBV | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 26.00 | 5.33 | +20.67 | SYRE | /balance-sheet <GO> |
| Piotroski F-Score Quality | 5/9 | 7/9 | -2.00 | ABBV | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | 6.50% | 7.40% | -0.90 | SYRE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 59.1 | 72.8 | -13.72 | ABBV | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | 0.89 | 1.15 | -0.26 | ABBV | /macro-sensitivity <GO> |
| Forward P/E Multiple | 22.0x | 113.1x | -91.10 | SYRE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $10.33B | $513.86B | -$503.53B | ABBV | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | SYRE REV | ABBV REV | SYRE GROSS % | ABBV GROSS % | SYRE FCF | ABBV FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $0 | $61.16B | — | 70.2% | -$169.3M | $17.82B |
| FY 2024 | $0 | $56.33B | — | 70.0% | -$157.4M | $17.83B |
| FY 2023 | $886.0K | $54.32B | 44.0% | 44.0% | -$99.9M | $20.39B |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
SYRE // BETA 0.89
ABBV // BETA 1.15