Stock Ratings / Health Care / GPCR / insiders

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Structure Therapeutics Inc. (GPCR) Insider, 13F Hedge Fund & Politician Buy/Sell Thermometer

Q: Where is GPCR trading relative to its 50-day, 200-day, and 52-week technical levels?

GPCR last traded at $21.94 (+2.14% on volume of 929,537 shares), positioning the stock -34.39% below its 50-day simple moving average ($33.44) and -55.28% below its 200-day simple moving average ($49.06). Across its 52-week range of $20.50 to $94.90, GPCR sits at the 1.9% percentile with a 14-day RSI of 26.5 (OVERSOLD (<32)) and an implied next-earnings move of ±12.3% ($19.24 to $24.64).

Q: Are GPCR insiders and hedge funds buying or selling?

Roarable's SEC Form 4 and 13F Whale Thermometer currently classifies GPCR leadership and institutional positioning as: NET EXECUTIVE TRIMMING / PROFIT-TAKING.

$21.94 +2.14% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $21.98

Structure Therapeutics Inc. (GPCR) carries a Roarable Rating of D- (Sell) with 42/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

📊 Historical Track Record Warning: Scores below 50 (42/100 · D-) historically underperformed SPY in 71% of rolling 90-day windows →

ROARABLE D- • SELL / AVOID Cap $1.56B

📤 Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card

⚡ INSTANT AI QUANT PREVIEW • $0 FREE TIER Click Any Pre-Computed AI Quant Specialist Briefing on GPCR Below — or Connect Your Own ChatGPT / Claude

🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is GPCR stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

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As of 2026-11-01, Structure Therapeutics Inc. (NASDAQ: GPCR) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 42/100 at a spot price of $21.94 (+2.14% 1D, market cap $1.56B). Pillar breakdown: Fundamental Cash Engine 4/20, Institutional 13F & Options Flow 13/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 12/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, GPCR ranks #571 in composite RQD confidence.

✓ Pre-computed one-to-many AI Quant brief

🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does GPCR compare to PAHC and INVA in the Health Care sector?

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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), GPCR carries a Roarable D- (42/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -19.5%. By comparison, PAHC (Phibro Animal Health Corporation (Class A)) holds a C+ grade (68/100 RQD, P/E 32.7x, ROIC 9.9%, cap $1.58B) and INVA (Innoviva Inc.) posts a B grade (75/100 RQD, P/E N/A, ROIC 14.7%, cap $1.54B). Among the 5-stock peer group, PAHC leads on earnings multiple (32.7x) while INVA leads on capital efficiency (14.7% ROIC).

✓ Pre-computed one-to-many AI Quant brief

🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for GPCR?

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Per GPCR's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001888886), Structure Therapeutics Inc. generated $0 in revenue, -$141.2M in net income, and -$225.8M in free cash flow against $1.58B in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief

🤖 AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists — not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).

INTERACTIVE SCENARIO DECK:

🛡️ Portfolio Crash X-Ray

EXT / AFTER-HRS: $21.98 (+0.20%)🧬 Dilution Drag (+2.48% YoY Shares)⚙️ Cash Engine: 4/20 (E) • 0% FCF Margin

Verify 90D Bucket Audit →

📊 Historical Track Record Warning: Scores below 50 (42/100 · D-) historically underperformed SPY in 71% of rolling 90-day windows (-7.0% avg 90D alpha vs SPY • 29.0% hit rate).

Audit Bucket Track Record →

RQD QUANT TACHOMETERSELL / AVOID • D-

3-of-3 JEV AI Jury Bearish Warning

Cash

SEC

Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw E · Rk D+

Each axis scored 0–20

12M PRICE TARGET CONE-7.2% Base Target

WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for GPCR)Realized 20D OHLCV Swing Band: ±12.3%

Deterministic 5-Pillar Attribution (42/100 Composite)

🔍 WHY GPCR SCORES 42/100 (D-) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag

▲ #1 Bullish Driver: Whale & Options Positioning+13/20 pts (31% of score)

20D Institutional Volume Accumulation (±12.3% realized swing band)

▲ #2 Bullish Driver: Macro Regime Fit+12/20 pts (29% of score)

FRED Regime × Technicals: 2% of 52W Range • RSI-14 at 26.5 (OVERSOLD (<32))

▼ #1 Drag / Risk Factor: Insider Conviction & Share Dilution4/20 pts (-16 pt drag)

Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current

Q1 (-3Q)

Grade C-$25.54-17.5% Next Q

Q2 (-2Q)

Grade D$21.08+0.5% Next Q

Q3 (-1Q)

Grade D$21.19+3.5% Next Q

Current

Grade D-$21.94-7% Hist 90D α

Trajectory: C- (50) → D- (42)Full Audit →

⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

⚔️ Adversarial Opposing Case: What Could Spark a GPCR Turnaround Squeeze

Gideon Ashmere Forensic Desk →

While GPCR currently carries a cautious 42/100 (D-) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

🚀 Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

🚀 Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($33.44) and Max Pain ($23.04) forces dealer call-delta covering toward $99.65.

🚀 Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $GPCR• $2.4M Crowd Pool • Kalshi / Polymarket Composite

Contract: “GPCR Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”

YES 42%NO 58%Trade / Inspect Odds →

SEC FORM 4 × 13F HEDGE FUNDS × CONGRESSIONAL STOCK ACT

GPCR Smart-Money Thermometer: NET EXECUTIVE TRIMMING / PROFIT-TAKING

Explore All 13F & Congress Whales →

▲ Disclosed Buys: 0 ($0)▼ Disclosed Sales: 0 ($0)

Wide-Open SEC Form 4, 13F & Congressional Disclosure Ledger (GPCR)

No recent open-market Form 4 cluster sales or emergency dumps flagged on GPCR. Visit the Global 13F & Congressional Whale Ledger for cross-market smart-money filings.

ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring GPCR)

✓Walkthrough of GPCR's RQD Radar, SEC cash-conversion gap & downside invalidation levels
✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks

RQD INSIDER CLUB WAITLIST$49/YR PLANNED

Want Custom AI PineScript / Python Indicators & Priority Rating-Change Alerts?

Join Founding VIP Waitlist (No Card Required) →$100K Arena

GPCR // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: -47.07%🛡️ HOLDING TREND SUPPORT

2026-10-30O $21.59H $22.36L $21.07C $21.94VOL 695.9K

RES: $53.05SUP: $19.30SMA50: $33.44SMA200: $49.06

PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

GPCR Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

🦋 GPCR Butterfly Map → + Track GPCR →

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)

8.0%/yr Implied 5Y Growth

vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on GPCR today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for GPCR. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video

🎬 No recent verified company-specific video clip queued for GPCR today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →

DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (GPCR)

Health Care Rank #571 of 1016 ⚔️ PAHC vs GPCR Full Matrix →

1. Head-to-Head Health Care Peer Comparison (GPCR vs. PAHC, INVA, ETON, OCUL)

Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)

Across 1016 tracked Health Care securities in the Roarable RQD universe, Structure Therapeutics Inc. (GPCR) ranks #571 by composite RQD confidence (42/100, grade D-) and #301 by equity capitalization ($1.56B). Within this direct 5-issuer industry benchmark cohort, PAHC leads on earnings valuation at 32.7x trailing P/E, while INVA leads on capital efficiency and profitability with 14.7% ROIC and 74.8% gross margin. INVA currently holds the highest overall quantitative score in the immediate peer group at 75/100 (B) compared with GPCR at 42/100 (D-).

Ticker / Company	Roarable Grade	RQD Score	Trailing P/E	Gross Margin	ROIC	1D Change	Market Cap	Head-to-Head
GPCR ACTIVE Structure Therapeutics Inc.	D-	42/100	—	—	-19.5%	+2.14%	$1.56B	Benchmark Subject
PAHC Phibro Animal Health Corporation (Class A)	C+	68/100	32.7x	30.9%	9.9%	+2.59%	$1.58B	/pahc-vs-gpcr →
INVA Innoviva Inc.	B	75/100	—	74.8%	14.7%	+0.90%	$1.54B	/inva-vs-gpcr →
ETON Eton Pharmaceuticals Inc.	C	62/100	—	53.5%	-0.9%	+3.61%	$1.53B	/eton-vs-gpcr →
OCUL Ocular Therapeutix Inc.	D-	37/100	—	87.3%	-35.0%	+0.27%	$1.61B	/ocul-vs-gpcr →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001888886

In its most recent audited fiscal period (FY2025, filed 2025-12-31), Structure Therapeutics Inc. (GPCR) reported GAAP revenue of $0 (N/A vs. FY2024 revenue of $0 ) , GAAP net income of -$141.2M, operating cash flow of -$222.2M, and free cash flow of -$225.8M (-91.5% YoY). On the balance sheet, GPCR closed FY2025 with $1.58B in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 1/9).

Fiscal Period	Filing Date	Revenue	Net Income	Operating Cash Flow	Free Cash Flow	Total Assets	Total Debt
FY2025 (FY)	2025-12-31	$0	-$141.2M	-$222.2M	-$225.8M	$1.58B	—
FY2024 (FY)	2024-12-31	$0	-$122.5M	-$116.6M	-$117.9M	$903.3M	—
FY2023 (FY)	2023-12-31	$0	-$89.6M	-$79.5M	-$79.5M	—	—

3. GPCR Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is GPCR stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

How does GPCR compare to PAHC and INVA in the Health Care sector?

What are the biggest fundamental strengths and SEC risk factors for GPCR?

Where is GPCR trading relative to its 50-day, 200-day, and 52-week technical levels?

GPCR last traded at $21.94 (+2.14% on volume of 929,537 shares), positioning the stock -34.39% below its 50-day simple moving average ($33.44) and -55.28% below its 200-day simple moving average ($49.06). Across its 52-week range of $20.50 to $94.90, GPCR sits at the 1.9% percentile with a 14-day RSI of 26.5 (OVERSOLD (<32)) and an implied next-earnings move of ±12.3% ($19.24 to $24.64).

GPCR Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS • SEC EDGAR × CBOE × FRED

Are GPCR insiders and hedge funds buying or selling?

Roarable's SEC Form 4 and 13F Whale Thermometer currently classifies GPCR leadership and institutional positioning as: NET EXECUTIVE TRIMMING / PROFIT-TAKING.

Direct Sub-Reports: GPCR RQD Cockpit GPCR 12M Forecast GPCR Earnings & Move GPCR Dividends & DRIP GPCR Insiders & 13F GPCR Whale Options GPCR Profit Sankey GPCR News & Why