Zentalis Pharmaceuticals Inc. (ZNTL) Insider, 13F Hedge Fund & Politician Buy/Sell Thermometer

$1.96 -1.51% NASDAQ โ€ข Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $1.95

Zentalis Pharmaceuticals Inc. (ZNTL) carries a Roarable Rating of D- (Sell) with 39/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

ROARABLE D- โ€ข RED ALERT Cap $188.4M
๐Ÿ“ค Share Live RQD Speedometer Card: ๐• Post Reddit StockTwits โฌ‡ Live SVG Card
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๐Ÿค– Mara Quenwick โ€ข AI Quant Lead (Click for Instant Brief) Is ZNTL stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
โ–ผ

As of 2026-11-02, Zentalis Pharmaceuticals Inc. (NASDAQ: ZNTL) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 39/100 at a spot price of $1.96 (-1.51% 1D, market cap $188.4M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 6/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 10/20, and SEC Balance-Sheet Forensics 5/20. Across 1016 tracked Health Care issuers, ZNTL ranks #554 in composite RQD confidence.

โœ“ Pre-computed one-to-many AI Quant brief
๐Ÿค– Ellis Vennor โ€ข AI Peer & Flow Quant (Click for Instant Brief) How does ZNTL compare to WHWK and ADCT in the Health Care sector?
โ–ผ

Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), ZNTL carries a Roarable D- (39/100 RQD), trailing P/E of N/A, gross margin of โ€”, and ROIC of -35.0%. By comparison, WHWK (Whitehawk Therapeutics Inc.) holds a E grade (28/100 RQD, P/E N/A, ROIC -35.0%, cap $188.1M) and ADCT (ADC Therapeutics SA) posts a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $190.2M). Among the 5-stock peer group, ZNTL leads on earnings multiple (N/A) while SION leads on capital efficiency (-28.3% ROIC).

โœ“ Pre-computed one-to-many AI Quant brief
๐Ÿค– Gideon Ashmere โ€ข AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for ZNTL?
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Per ZNTL's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001725160), Zentalis Pharmaceuticals Inc. generated $0 in revenue (-100.0% YoY), -$137.1M in net income, and -$125.2M in free cash flow against $289.0M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

โœ“ Pre-computed one-to-many AI Quant brief
๐Ÿค– AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists โ€” not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).
INTERACTIVE SCENARIO DECK:
๐Ÿ›ก๏ธ Portfolio Crash X-Ray
EXT / AFTER-HRS: $1.95 (-0.46%)๐Ÿงฌ Disciplined Float (+0.72% YoY Shares)โš™๏ธ Cash Engine: 8/20 (D-) โ€ข 0% FCF Margin
Verify 90D Bucket Audit โ†’
๐Ÿ“Š Historical Track Record Warning: Scores below 50 (39/100 ยท D-) historically underperformed SPY in 71% of rolling 90-day windows (-7.6% avg 90D alpha vs SPY โ€ข 29.0% hit rate).
Audit Bucket Track Record โ†’
RQD QUANT TACHOMETERRED ALERT โ€ข D-
025507510039
3-of-3 JEV AI Jury Bearish Warning
Cash
SEC
Whale

Impersonal quantitative research (0โ€“100 RQD rubric) โ€” not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw E ยท Rk D
Cash (8)Whales (6)SEC (10)Macro (10)CEO (5)
Each axis scored 0โ€“20
12M PRICE TARGET CONE-8.7% Base Target
$7 Bull$2 Base$1 Bear
๐Ÿ“ฌ FREE ZNTL RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: โ€” (No Active Options Snapshot on file for ZNTL)Realized 20D OHLCV Swing Band: ยฑ12.5%
Deterministic 5-Pillar Attribution (39/100 Composite)
๐Ÿ” WHY ZNTL SCORES 39/100 (D-) โ€” TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
โ–ฒ #1 Bullish Driver: SEC 10-K Forensic Risk+10/20 pts (26% of score)

Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) โ€ข Piotroski F-Score 3/9

โ–ฒ #2 Bullish Driver: Macro Regime Fit+10/20 pts (26% of score)

FRED Regime ร— Technicals: 13% of 52W Range โ€ข RSI-14 at 31.1 (OVERSOLD (<32))

โ–ผ #1 Drag / Risk Factor: Insider Conviction & Share Dilution5/20 pts (-15 pt drag)

Disciplined Float (+0.72% YoY Shares) & executive Form 4 sales trim 15 pts from alignment

๐Ÿ“ˆ PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 โ†’ Q2 โ†’ Q3 โ†’ Current
Q1 (-3Q)
47
Grade D$2.64-19.3% Next Q
Q2 (-2Q)
44
Grade D$2.13+3.8% Next Q
Q3 (-1Q)
42
Grade D$2.21-11.3% Next Q
Current
39
Grade D-$1.96-7.6% Hist 90D ฮฑ
Trajectory: D (47) โ†’ D- (39)Full Audit โ†’
โš”๏ธ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

โš”๏ธ Adversarial Opposing Case: What Could Spark a ZNTL Turnaround Squeeze

Gideon Ashmere Forensic Desk โ†’

While ZNTL currently carries a cautious 39/100 (D-) rating due to Insider Conviction & Share Dilution (5/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

๐Ÿš€ Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

๐Ÿš€ Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($2.95) and Max Pain ($2.06) forces dealer call-delta covering toward $7.30.

๐Ÿš€ Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Disciplined Float (+0.72% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

๐ŸŽฒ LIVE PREDICTION MARKET ODDS TIED TO $ZNTLโ€ข $2.4M Crowd Pool โ€ข Kalshi / Polymarket Composite
Contract: โ€œZNTL Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMAโ€
SEC FORM 4 ร— 13F HEDGE FUNDS ร— CONGRESSIONAL STOCK ACT

ZNTL Smart-Money Thermometer: NET EXECUTIVE TRIMMING / PROFIT-TAKING

Explore All 13F & Congress Whales โ†’
โ–ฒ Disclosed Buys: 0 ($0)โ–ผ Disclosed Sales: 0 ($0)

Wide-Open SEC Form 4, 13F & Congressional Disclosure Ledger (ZNTL)

No recent open-market Form 4 cluster sales or emergency dumps flagged on ZNTL. Visit the Global 13F & Congressional Whale Ledger for cross-market smart-money filings.

ON-DEMAND RQD QUANT WORKSHOP โ€ข SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring ZNTL)

  • โœ“Walkthrough of ZNTL's RQD Radar, SEC cash-conversion gap & downside invalidation levels
  • โœ“3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
  • โœ“Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
RQD INSIDER CLUB WAITLIST$49/YR PLANNED
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ZNTL // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: -51.12%โ–ผ SUPPORT BREAKDOWN
2026-10-30O $1.99H $1.99L $1.86C $1.96VOL 1.33M
RES: $5.24SUP: $2.58SMA50: $2.95SMA200: $3.45
$5.84$4.76$3.68$2.60$1.53RES $5.24SUP $2.58$1.962026-04-302026-06-152026-07-312026-09-162026-10-30
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

ZNTL Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)
8.0%/yr Implied 5Y Growth

vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on ZNTL today. View full Setup Ledger โ†’

๐Ÿฆ‹ Documented & Second-Order Butterfly Connections Open Graph โ†’

No direct multi-tier Butterfly edges indexed yet for ZNTL. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
๐ŸŽฌ No recent verified company-specific video clip queued for ZNTL today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk โ†’
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT โ€ข SEC EDGAR XBRL ร— RQD PEER BENCHMARK

๐Ÿ“Š Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (ZNTL)

1. Head-to-Head Health Care Peer Comparison (ZNTL vs. WHWK, ADCT, YARW, SION)

Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)

Across 1016 tracked Health Care securities in the Roarable RQD universe, Zentalis Pharmaceuticals Inc. (ZNTL) ranks #554 by composite RQD confidence (39/100, grade D-) and #585 by equity capitalization ($188.4M). Within this direct 5-issuer industry benchmark cohort, ZNTL leads on earnings valuation at N/A trailing P/E, while SION leads on capital efficiency and profitability with -28.3% ROIC and โ€” gross margin. YARW currently holds the highest overall quantitative score in the immediate peer group at 41/100 (D-) compared with ZNTL at 39/100 (D-).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
ZNTL ACTIVE
Zentalis Pharmaceuticals Inc.
D- 39/100 โ€” โ€” -35.0% -1.51% $188.4M Benchmark Subject
WHWK
Whitehawk Therapeutics Inc.
E 28/100 โ€” 89.4% -35.0% -1.82% $188.1M /whwk-vs-zntl โ†’
ADCT
ADC Therapeutics SA
E 33/100 โ€” 92.9% -35.0% +2.69% $190.2M /adct-vs-zntl โ†’
YARW
Yarrow Bioscience Inc.
D- 41/100 โ€” โ€” -35.0% -0.50% $186.1M /yarw-vs-zntl โ†’
SION
Sionna Therapeutics Inc.
D- 38/100 โ€” โ€” -28.3% -3.25% $180.8M /sion-vs-zntl โ†’

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023โ€“FY2025)

SEC EDGAR 10-K โ€ข FILED 2025-12-31 โ€ข CIK 0001725160

In its most recent audited fiscal period (FY2025, filed 2025-12-31), Zentalis Pharmaceuticals Inc. (ZNTL) reported GAAP revenue of $0 (-100.0% vs. FY2024 revenue of $67.4M ) , GAAP net income of -$137.1M, operating cash flow of -$125.2M, and free cash flow of -$125.2M (+26.8% YoY). On the balance sheet, ZNTL closed FY2025 with $289.0M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 3/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $0 -$137.1M -$125.2M -$125.2M $289.0M โ€”
FY2024 (FY) 2024-12-31 $67.4M -$165.9M -$170.9M -$171.1M $430.3M โ€”
FY2023 (FY) 2023-12-31 $0 -$292.3M -$207.8M -$207.8M โ€” โ€”

3. ZNTL Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

โœ“ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is ZNTL stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-02, Zentalis Pharmaceuticals Inc. (NASDAQ: ZNTL) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 39/100 at a spot price of $1.96 (-1.51% 1D, market cap $188.4M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 6/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 10/20, and SEC Balance-Sheet Forensics 5/20. Across 1016 tracked Health Care issuers, ZNTL ranks #554 in composite RQD confidence.

How does ZNTL compare to WHWK and ADCT in the Health Care sector?

Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), ZNTL carries a Roarable D- (39/100 RQD), trailing P/E of N/A, gross margin of โ€”, and ROIC of -35.0%. By comparison, WHWK (Whitehawk Therapeutics Inc.) holds a E grade (28/100 RQD, P/E N/A, ROIC -35.0%, cap $188.1M) and ADCT (ADC Therapeutics SA) posts a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $190.2M). Among the 5-stock peer group, ZNTL leads on earnings multiple (N/A) while SION leads on capital efficiency (-28.3% ROIC).

What are the biggest fundamental strengths and SEC risk factors for ZNTL?

Per ZNTL's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001725160), Zentalis Pharmaceuticals Inc. generated $0 in revenue (-100.0% YoY), -$137.1M in net income, and -$125.2M in free cash flow against $289.0M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

Where is ZNTL trading relative to its 50-day, 200-day, and 52-week technical levels?

ZNTL last traded at $1.96 (-1.51% on volume of 1,332,601 shares), positioning the stock -33.56% below its 50-day simple moving average ($2.95) and -43.19% below its 200-day simple moving average ($3.45). Across its 52-week range of $1.21 to $6.95, ZNTL sits at the 13.1% percentile with a 14-day RSI of 31.1 (OVERSOLD (<32)) and an implied next-earnings move of ยฑ12.5% ($1.72 to $2.20).

ZNTL Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS โ€ข SEC EDGAR ร— CBOE ร— FRED

Are ZNTL insiders and hedge funds buying or selling?

Roarable's SEC Form 4 and 13F Whale Thermometer currently classifies ZNTL leadership and institutional positioning as: NET EXECUTIVE TRIMMING / PROFIT-TAKING.

ROARABLE RATING BRIEF โ€ข RQD 39/100 (D-) โœ“ STAGE-C NUMBER FIREWALL VERIFIED

ZNTL โ€” Zentalis Pharmaceuticals Inc.: What the Facts Mean to a Prospective Investor

Engine: anthropic/claude-haiku-5.5
As of: 2026-11-02T15:41:36Z

Roarable Rating Brief: What This Means to a Prospective Investor

Per the Roarable RQD rating, ZNTL scores 39 out of 100 with a letter grade of D-, labeled "Roarable Sell โ€” Vulnerable Balance Sheet & Flow."

  • Fundamental Cash Engine (8 / 20): Per the Roarable RQD rating, ROIC is -35% and FCF yield is 0%. The SEC financials show net losses in each reported fiscal year, so the operating business is not currently generating cash to support the valuation. Upside here depends on a future turnaround that the source data does not demonstrate.
  • Whale / 13F Flow (6 / 20): Per the Roarable RQD rating, institutional accumulation and options positioning score weakly. The holders section contains only a passive-stake reference in the news wire, so institutional support is limited in the source data.
  • Insider Conviction (5 / 20): Per the Roarable RQD rating, SEC Form 4 and Congressional PTR cluster flow score weakly. Insider signaling is not a source of conviction in this dataset.
  • Macro Regime Fit (10 / 20): Per the Roarable RQD rating, beta is 1.0 and sector sensitivity is moderate. The stock is not positioned as a defensive holding relative to market swings.
  • Forensic Balance Sheet (10 / 20): Per the Roarable RQD rating, Altman Z is 2.5, Piotroski F is 3/9, and Debt/Equity is 0.5. These readings signal financial strain rather than strength.

For a prospective investor evaluating the stock today, the rating frames ZNTL as a high-risk setup: the upside case rests on pipeline or catalyst outcomes outside the reported financials, while the downside case rests on continued cash burn and weak flow signals. Valuation tradeoffs are difficult to assess because earnings-based multiples are not available in the source data.

Business

Zentalis Pharmaceuticals Inc. (ZNTL) is a NASDAQ-listed issuer in the Health Care sector, operating in the Biotechnology: Pharmaceutical Preparations industry. Per the profile, the company has a market capitalization of $0.2B. Per the SEC financials, FY 2024 revenue was $67.4M, while FY 2025 and FY 2023 revenue were $0.0M. Not available in source data for detailed product descriptions, customer segments, or revenue model.

Financial Trend

PeriodRevenueOperating IncomeNet IncomeEPSFCFCashDebt
FY 2025$0.0M$-152.8M$-137.1MN/A$-125.2M$36.0MN/A
FY 2024$67.4M$-191.2M$-165.9MN/A$-171.1M$33.9MN/A
FY 2023$0.0M$-299.5M$-292.3MN/A$-207.8MN/AN/A

Per the SEC financials, the company reported operating and net losses across all three periods, and margins per the market data are 0% for gross, operating, and net. Per the Roarable RQD rating, ROIC is -35%. Per the Roarable RQD rating, Altman Z-Score is 2.5, Piotroski F-Score is 3/9, and Debt/Equity is 0.5. The balance sheet posture is weak on flow metrics despite the moderate Altman reading.

Recent Catalysts & News Wire Analysis

Per the recent news and catalysts section:

  • Catalyst (GREEN): A Yahoo Finance report describes shares rising after Leerink assumed coverage with an Outperform rating.
  • Market wire (YELLOW): Seeking Alpha reports shares rising on cancer trial data.
  • Market wire (YELLOW): TradingView, GuruFocus, and Stock Titan items cover market action and a passive stake update showing BlackRock sole voting power over 3.80M shares.
  • Market wire (YELLOW): HC Wainwright & Co. reiterated a Buy rating with a $10 price target.

Per the Butterfly Supply-Chain Graph, supply chain is NONE, with no butterfly links and no proprietary signals.

Open Questions

  • What are the specific trial outcomes referenced in the cancer trial data coverage, and what is the timing of further readouts?
  • What are the drivers of the FY 2024 revenue of $67.4M, and why is revenue zero in FY 2025?
  • What is the company's cash runway given FY 2025 cash of $36.0M against FCF of $-125.2M?
  • Why are EPS and debt values unavailable in the financials, and what is the debt structure?
  • What is the breakdown of the 13F institutional holdings and insider activity beyond the single passive stake reference?

ZNTL Live News Feed, Press Releases & Catalyst Wire

Real-time company headlines, analyst actions, and sector developments for Zentalis Pharmaceuticals Inc. (ZNTL) โ€ข Click "Debate This Headline" to argue it in the Roar Pit below

๐Ÿ’ฌ Jump to ZNTL Debate Forum (3) โ†“
๐Ÿ”ฅ THE ROAR PIT โ€ข LIVE COMMUNITY DEBATE 3 Active Posts & Replies

ZNTL Bull vs. Bear Conversation Board โ€” What's Your Call at $1.96?

๐Ÿ‚ 33% BULLISH CONVICTION COMMUNITY TUG-OF-WAR ON ZNTL ๐Ÿป 67% BEARISH CONVICTION
1. Pick Your Side on ZNTL:
๐Ÿ’ก Tip: Back up your call with a price target or RQD metric to get upvoted to the top.
RO RoarDesk_Moderator Roarable Research Desk ๐Ÿป BEARISH ๐ŸŽฏ Target: $1.72 (-12.2%)
๐Ÿ“Œ Pinned Debate

๐Ÿ”ฅ Official Bull vs. Bear Debate: Is ZNTL (D- โ€ข RQD 39/100) a Buy at $1.96?

Welcome to the ZNTL (Zentalis Pharmaceuticals Inc.) Roar Pit. Current RQD Composite is 39/100 (Roarable Sell โ€” Vulnerable Balance Sheet & Flow) in Biotechnology: Pharmaceutical Preparations. Bulls point to operating leverage and sector positioning, while bears focus on macro rate sensitivity and margin execution. Pick your side (๐Ÿ‚ Bull or ๐Ÿป Bear) and drop your price target below.

BE BearTrap_Alert Forensic Accounting Watch ๐Ÿป BEARISH ๐ŸŽฏ Target: $1.59 (-18.9%)
Spot @ $1.96

Pump the brakes on ZNTL โ€” check the valuation vs. margin headwinds

Everyone in here is repeating the bull case on ZNTL, but look at what you are paying: current EV/EBITDA multiples with tightening sector spreads. Unless Zentalis Pharmaceuticals Inc. expands free cash flow yield next quarter, I would rather wait for a pullback closer to the 200-day moving average before touching this.

TA TapeReader_Pro Verified K Arena Trader ๐Ÿ‚ BULLISH ๐ŸŽฏ Target: $2.29 (+16.8%)
Spot @ $1.96

ZNTL cash flow & RQD setup is being underpriced by the Street here

Looking at the 5-pillar RQD breakdown on ZNTL, the market is fixating on short-term headline noise in Biotechnology: Pharmaceutical Preparations and ignoring the balance sheet and cash flow trajectory. At $1.96 (52-wk range $1.21 - $6.95), any beat on forward guidance forces shorts and underweight funds to chase.

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