Alector Inc. (ALEC) carries a Roarable Rating of E (Strong Sell) with 33/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
As of 2026-11-02, Alector Inc. (NASDAQ: ALEC) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 33/100 at a spot price of $2.21 (-1.34% 1D, market cap $332.1M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 13/20, Executive Insider Alignment 3/20, FRED Macro Regime Fit 12/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, ALEC ranks #741 in composite RQD confidence.
Within the Health Care sector (Biotechnology: Biological Products (No Diagnostic Substances)), ALEC carries a Roarable E (33/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, XFOR (X4 Pharmaceuticals Inc.) holds a E grade (29/100 RQD, P/E N/A, ROIC -35.0%, cap $333.1M) and SCTX (Scribe Therapeutics Inc.) posts a D grade (44/100 RQD, P/E N/A, ROIC —, cap $330.2M). Among the 5-stock peer group, ALEC leads on earnings multiple (N/A) while ALEC leads on capital efficiency (-35.0% ROIC).
Per ALEC's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001653087), Alector Inc. generated $21.0M in revenue (-79.1% YoY), -$143.0M in net income, and -$184.1M in free cash flow against $293.2M in total assets and $9.3M in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
20D Institutional Volume Accumulation (±12.5% realized swing band)
FRED Regime × Technicals: 67% of 52W Range • RSI-14 at 61.6 (BULLISH MOMENTUM)
Dilution Drag (+1.28% YoY Shares) & executive Form 4 sales trim 16 pts from alignment
While ALEC currently carries a cautious 33/100 (E) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($2.08) and Max Pain ($2.32) forces dealer call-delta covering toward $2.90.
Forensic Repair Trigger: Halting share dilution (Dilution Drag (+1.28% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Alector Inc. (ALEC) slipped -1.34% to $2.21, trading at 67% of its 52-week range ($1.09 – $2.76). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
Moderna (MRNA) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.
Alector (ALEC) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.
Alector (ALEC) holds steady despite trial failures, pivoting to ABC platform and Roche deal extending cash to 2029.
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. -65.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on ALEC today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for ALEC. Explore sector supply chains on /butterfly.
Across 1016 tracked Health Care securities in the Roarable RQD universe, Alector Inc. (ALEC) ranks #741 by composite RQD confidence (33/100, grade E) and #508 by equity capitalization ($332.1M). Within this direct 5-issuer industry benchmark cohort, ALEC leads on earnings valuation at N/A trailing P/E, while ALEC leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. SCTX currently holds the highest overall quantitative score in the immediate peer group at 44/100 (D) compared with ALEC at 33/100 (E).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| ALEC
ACTIVE
Alector Inc. | E | 33/100 | — | — | -35.0% | -1.34% | $332.1M | Benchmark Subject |
| XFOR X4 Pharmaceuticals Inc. | E | 29/100 | — | 83.6% | -35.0% | -0.30% | $333.1M | /xfor-vs-alec → |
| SCTX Scribe Therapeutics Inc. | D | 44/100 | — | — | — | -11.58% | $330.2M | /sctx-vs-alec → |
| IRLA IRulya Therapeutics Inc. | E | 33/100 | — | — | -35.0% | +4.21% | $342.8M | /irla-vs-alec → |
| AGEN Agenus Inc. | E | 30/100 | — | 96.0% | -35.0% | -3.53% | $320.2M | /agen-vs-alec → |
In its most recent audited fiscal period (FY2025, filed 2025-12-31), Alector Inc. (ALEC) reported GAAP revenue of $21.0M (-79.1% vs. FY2024 revenue of $100.6M , and -78.3% cumulative change since FY2023) , GAAP net income of -$143.0M, operating cash flow of -$184.0M, and free cash flow of -$184.1M (+20.4% YoY). On the balance sheet, ALEC closed FY2025 with $293.2M in total assets against $9.3M in total debt (Altman Z-Score: 0.20, Piotroski F-Score: 2/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $21.0M | -$143.0M | -$184.0M | -$184.1M | $293.2M | $9.3M |
| FY2024 (FY) | 2024-12-31 | $100.6M | -$119.0M | -$229.9M | -$231.2M | $468.3M | $9.4M |
| FY2023 (FY) | 2023-12-31 | $97.1M | -$130.0M | -$184.2M | -$184.2M | — | — |
As of 2026-11-02, Alector Inc. (NASDAQ: ALEC) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 33/100 at a spot price of $2.21 (-1.34% 1D, market cap $332.1M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 13/20, Executive Insider Alignment 3/20, FRED Macro Regime Fit 12/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, ALEC ranks #741 in composite RQD confidence.
Within the Health Care sector (Biotechnology: Biological Products (No Diagnostic Substances)), ALEC carries a Roarable E (33/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, XFOR (X4 Pharmaceuticals Inc.) holds a E grade (29/100 RQD, P/E N/A, ROIC -35.0%, cap $333.1M) and SCTX (Scribe Therapeutics Inc.) posts a D grade (44/100 RQD, P/E N/A, ROIC —, cap $330.2M). Among the 5-stock peer group, ALEC leads on earnings multiple (N/A) while ALEC leads on capital efficiency (-35.0% ROIC).
Per ALEC's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001653087), Alector Inc. generated $21.0M in revenue (-79.1% YoY), -$143.0M in net income, and -$184.1M in free cash flow against $293.2M in total assets and $9.3M in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
ALEC last traded at $2.21 (-1.34% on volume of 1,111,257 shares), positioning the stock +6.25% above its 50-day simple moving average ($2.08) and +8.87% above its 200-day simple moving average ($2.03). Across its 52-week range of $1.09 to $2.76, ALEC sits at the 67.1% percentile with a 14-day RSI of 61.6 (BULLISH MOMENTUM) and an implied next-earnings move of ±12.5% ($1.93 to $2.49).
Why ALEC Stock slipped -1.34% Today — RQD Quant Desk Flash. Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
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