Yahoo! Finance Canada report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Why ADAG Stock dropped -6.34% Today — RQD Quant Desk Flash
Adagene Inc. (ADAG) carries a Roarable Rating of E (Strong Sell) with 30/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is ADAG stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-02, Adagene Inc. (NASDAQ: ADAG) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 30/100 at a spot price of $2.51 (-6.34% 1D, market cap $177.0M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 8/20, Executive Insider Alignment 8/20, FRED Macro Regime Fit 8/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, ADAG ranks #852 in composite RQD confidence.
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does ADAG compare to ANTX and ORMP in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), ADAG carries a Roarable E (30/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, ANTX (AN2 Therapeutics Inc.) holds a D grade (46/100 RQD, P/E N/A, ROIC -35.0%, cap $177.0M) and ORMP (Oramed Pharmaceuticals Inc.) posts a D- grade (41/100 RQD, P/E N/A, ROIC -7.8%, cap $176.0M). Among the 5-stock peer group, ADAG leads on earnings multiple (N/A) while ORMP leads on capital efficiency (-7.8% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for ADAG?
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Per ADAG's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001818838), Adagene Inc. generated $7.7M in revenue (+7332.8% YoY), -$17.6M in net income, and -$15.7M in free cash flow against $78.3M in total assets and $1.1M in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
20D Institutional Volume Accumulation (±12.5% realized swing band)
Altman Z-Score 0.20 (DISTRESS RISK (<1.8)) • Piotroski F-Score 5/9
Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment
⚔️ Adversarial Opposing Case: What Could Spark a ADAG Turnaround Squeeze
While ADAG currently carries a cautious 30/100 (E) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($3.05) and Max Pain ($2.64) forces dealer call-delta covering toward $5.09.
Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why ADAG Stock dropped -6.34% Today — RQD Quant Desk Flash
Adagene Inc. (ADAG) dropped -6.34% to $2.51, trading at 34% of its 52-week range ($1.3 – $4.85). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 34% of its 52-week range ($1.3 – $4.85) with RSI-14 at 43.5 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±12.5% around $2.51 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable E (Strong Sell) backed by 52% gross margin and $0 annual free cash flow.
StockInvest.us report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
https://www.dars.gov.et/ report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Traders Union report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Incyte (NasdaqGS: INCY) and Adagene have started first patient dosing in a Phase 1 trial combining INCA33890 with muzastotug for microsatellite stable colorectal cancer. The early stage study is testing the investigation
Phase 1 study to evaluate the combination of muzastotug, a masked anti-CTLA-4 SAFEbody, and INCA33890, Incyte’s TGFβR2 × PD-1 bispecific antibody, in 3L MSS CRC patients with and without liver metastases SAN DIEGO and SU
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring ADAG)
- ✓Walkthrough of ADAG's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
ADAG Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. +180.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on ADAG today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for ADAG. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (ADAG)
1. Head-to-Head Health Care Peer Comparison (ADAG vs. ANTX, ORMP, UPB, SION)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1016 tracked Health Care securities in the Roarable RQD universe, Adagene Inc. (ADAG) ranks #852 by composite RQD confidence (30/100, grade E) and #594 by equity capitalization ($177.0M). Within this direct 5-issuer industry benchmark cohort, ADAG leads on earnings valuation at N/A trailing P/E, while ORMP leads on capital efficiency and profitability with -7.8% ROIC and 0.7% gross margin. ANTX currently holds the highest overall quantitative score in the immediate peer group at 46/100 (D) compared with ADAG at 30/100 (E).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| ADAG
ACTIVE
Adagene Inc. | E | 30/100 | — | — | -35.0% | -6.34% | $177.0M | Benchmark Subject |
| ANTX AN2 Therapeutics Inc. | D | 46/100 | — | — | -35.0% | -3.41% | $177.0M | /antx-vs-adag → |
| ORMP Oramed Pharmaceuticals Inc. | D- | 41/100 | — | 0.7% | -7.8% | -2.84% | $176.0M | /ormp-vs-adag → |
| UPB Upstream Bio Inc. | D- | 42/100 | — | — | -35.0% | +4.28% | $179.1M | /upb-vs-adag → |
| SION Sionna Therapeutics Inc. | D- | 38/100 | — | — | -28.3% | -3.25% | $180.8M | /sion-vs-adag → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001818838In its most recent audited fiscal period (FY2025, filed 2025-12-31), Adagene Inc. (ADAG) reported GAAP revenue of $7.7M (+7332.8% vs. FY2024 revenue of $103.2K , and -57.6% cumulative change since FY2023) , GAAP net income of -$17.6M, operating cash flow of -$15.7M, and free cash flow of -$15.7M (+47.3% YoY). On the balance sheet, ADAG closed FY2025 with $78.3M in total assets against $1.1M in total debt (Altman Z-Score: 0.20, Piotroski F-Score: 5/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $7.7M | -$17.6M | -$15.7M | -$15.7M | $78.3M | $1.1M |
| FY2024 (FY) | 2024-12-31 | $103.2K | -$33.4M | -$29.7M | -$29.7M | $89.3M | $417.3K |
| FY2023 (FY) | 2023-12-31 | $18.1M | -$18.9M | -$28.5M | -$28.5M | — | — |
3. ADAG Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs ADAG stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-02, Adagene Inc. (NASDAQ: ADAG) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 30/100 at a spot price of $2.51 (-6.34% 1D, market cap $177.0M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 8/20, Executive Insider Alignment 8/20, FRED Macro Regime Fit 8/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, ADAG ranks #852 in composite RQD confidence.
How does ADAG compare to ANTX and ORMP in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), ADAG carries a Roarable E (30/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, ANTX (AN2 Therapeutics Inc.) holds a D grade (46/100 RQD, P/E N/A, ROIC -35.0%, cap $177.0M) and ORMP (Oramed Pharmaceuticals Inc.) posts a D- grade (41/100 RQD, P/E N/A, ROIC -7.8%, cap $176.0M). Among the 5-stock peer group, ADAG leads on earnings multiple (N/A) while ORMP leads on capital efficiency (-7.8% ROIC).
What are the biggest fundamental strengths and SEC risk factors for ADAG?
Per ADAG's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001818838), Adagene Inc. generated $7.7M in revenue (+7332.8% YoY), -$17.6M in net income, and -$15.7M in free cash flow against $78.3M in total assets and $1.1M in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Where is ADAG trading relative to its 50-day, 200-day, and 52-week technical levels?
ADAG last traded at $2.51 (-6.34% on volume of 79,692 shares), positioning the stock -17.70% below its 50-day simple moving average ($3.05) and -26.61% below its 200-day simple moving average ($3.42). Across its 52-week range of $1.30 to $4.85, ADAG sits at the 34.1% percentile with a 14-day RSI of 43.5 (NEUTRAL RANGE) and an implied next-earnings move of ±12.5% ($2.20 to $2.82).
ADAG Investor FAQ & Complete 8-Part Research Index
100% OPEN ACCESS • SEC EDGAR × CBOE × FREDWhy is ADAG stock moving today?
Why ADAG Stock dropped -6.34% Today — RQD Quant Desk Flash. Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
ADAG — Adagene Inc.: What the Facts Mean to a Prospective Investor
Roarable Rating Brief: What This Means to a Prospective Investor
Per the Roarable RQD rating, ADAG scores 30 out of 100 with a letter grade of E, labeled "Roarable Strong Sell — Forensic Risk / Avoid." The five pillars are: Fundamental Cash Engine at 3/20 (ROIC -35%; FCF yield -8.85%), Whale 13F Flow at 8/20 (institutional accumulation and options positioning), Insider Conviction at 3/20 (SEC Form 4 and Congressional PTR cluster flow), Macro Regime Fit at 8/20 (Beta 1.0; sector sensitivity), and Forensic Balance Sheet at 8/20 (Altman Z 0.2; Piotroski F 5/9; Debt/Equity 0.03).
For a prospective investor, the weakest pillars are the cash engine and insider conviction, both scoring 3 of 20. The negative ROIC and negative FCF yield indicate the business is currently consuming capital rather than generating it, per the Roarable RQD rating and market data. The Altman Z-Score of 0.2 sits in the distress territory of the source's framing, and the Piotroski F-Score of 5/9 signals mixed rather than strong fundamental health. The low Debt/Equity of 0.03 is the most favorable forensic datapoint, indicating limited leverage, though the cash-burn trend is the central concern. Upside drivers would need to come from clinical or partnership catalysts rather than current earnings. Valuation tradeoffs are difficult to assess because P/E and EV/EBITDA are not available in source data.
Financial Trend
| Period | Revenue | Operating Income | Net Income | EPS | FCF | Cash | Debt |
|---|---|---|---|---|---|---|---|
| FY 2025 | $7.7M | $-21.4M | $-17.6M | N/A | $-15.7M | $74.5M | $1.1M |
| FY 2024 | $0.1M | $-36.0M | $-33.4M | N/A | $-29.7M | $85.2M | $0.4M |
| FY 2023 | $18.1M | $-23.7M | $-18.9M | N/A | $-28.5M | N/A | N/A |
Per the SEC financials, operating losses persisted across all three reported periods, with FY 2025 operating income at $-21.4M against revenue of $7.7M. Market data shows operating and net margins of -60%, a gross margin of 0%, and ROIC of -35%. The Altman Z-Score of 0.2 and Piotroski F-Score of 5/9 are reported in the Roarable RQD rating, alongside Debt/Equity of 0.03. Cash declined from $85.2M in FY 2024 to $74.5M in FY 2025 while debt rose from $0.4M to $1.1M.
Recent Catalysts & News Wire Analysis
Per the recent news wire, several items reference ADAG, all flagged YELLOW with impact label MARKET WIRE. Headlines include a Yahoo! Finance Canada market report, a StockInvest.us forecast, a TradingView estimates page, and a Stock Titan item reporting that the first patient has received two drugs together in a colorectal cancer study. A separate item reports HC Wainwright & Co. reiterating a Buy rating with a $7 price target. A further item reports shares slipping to $2.76 while testing the lower end of a recent range. The news feed contains no proprietary risk signals. Note that one item's summary field references an unrelated domain rather than a substantive description, and should be treated as unverified. The Butterfly supply-chain graph reports no proprietary signals.
Open Questions
- What is the company's cash runway given FY 2025 FCF of $-15.7M against a reported cash balance of $74.5M?
- What specific clinical programs, partnerships, or milestones drive revenue, and what is their timing?
- What explains the rise in debt from $0.4M to $1.1M between FY 2024 and FY 2025?
- Why are P/E, EPS, and EV/EBITDA unavailable, and what is the company's valuation on forward cash flow?
- What institutional or insider positioning exists, given that holder and analyst datasets are empty?
ADAG Live News Feed, Press Releases & Catalyst Wire
Real-time company headlines, analyst actions, and sector developments for Adagene Inc. (ADAG) • Click "Debate This Headline" to argue it in the Roar Pit below
Yahoo! Finance Canada report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
StockInvest.us report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
https://www.dars.gov.et/ report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Traders Union report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
ADAG Bull vs. Bear Conversation Board — What's Your Call at $2.51?
🔥 Official Bull vs. Bear Debate: Is ADAG (E • RQD 30/100) a Buy at $2.51?
Welcome to the ADAG (Adagene Inc.) Roar Pit. Current RQD Composite is 30/100 (Roarable Strong Sell — Forensic Risk / Avoid) in Biotechnology: Pharmaceutical Preparations. Bulls point to operating leverage and sector positioning, while bears focus on macro rate sensitivity and margin execution. Pick your side (🐂 Bull or 🐻 Bear) and drop your price target below.
Pump the brakes on ADAG — check the valuation vs. margin headwinds
Everyone in here is repeating the bull case on ADAG, but look at what you are paying: current EV/EBITDA multiples with tightening sector spreads. Unless Adagene Inc. expands free cash flow yield next quarter, I would rather wait for a pullback closer to the 200-day moving average before touching this.
ADAG cash flow & RQD setup is being underpriced by the Street here
Looking at the 5-pillar RQD breakdown on ADAG, the market is fixating on short-term headline noise in Biotechnology: Pharmaceutical Preparations and ignoring the balance sheet and cash flow trajectory. At $2.51 (52-wk range $1.30 - $4.85), any beat on forward guidance forces shorts and underweight funds to chase.