Castle Biosciences Inc. (CSTL) — RQD Stock Rating Cockpit

$38.51 +4.99% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $38.78

Castle Biosciences Inc. (CSTL) carries a Roarable Rating of C (Hold) with 63/100 RQD Confidence. The composite score sits in the neutral Hold band (59–69), meaning current holders don’t need to panic-sell while prospective buyers can wait for a move into the 70+ Buy zone.

ROARABLE C • HOLD / WATCH Cap $1.18B
📤 Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card
⚡ INSTANT AI QUANT PREVIEW • $0 FREE TIER Click Any Pre-Computed AI Quant Specialist Briefing on CSTL Below — or Connect Your Own ChatGPT / Claude
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is CSTL stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-02, Castle Biosciences Inc. (NASDAQ: CSTL) is rated C (Hold / HOLD) by Roarable's 5-pillar RQD engine with a composite confidence score of 63/100 at a spot price of $38.51 (+4.99% 1D, market cap $1.18B). Pillar breakdown: Fundamental Cash Engine 13/20, Institutional 13F & Options Flow 16/20, Executive Insider Alignment 14/20, FRED Macro Regime Fit 13/20, and SEC Balance-Sheet Forensics 7/20. Across 1016 tracked Health Care issuers, CSTL ranks #152 in composite RQD confidence.

✓ Pre-computed one-to-many AI Quant brief
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does CSTL compare to LMRI and TRUP in the Health Care sector?
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Within the Health Care sector (Medical Specialities), CSTL carries a Roarable C (63/100 RQD), trailing P/E of N/A, gross margin of 79.4%, and ROIC of -9.3%. By comparison, LMRI (Lumexa Imaging Holdings Inc.) holds a D+ grade (54/100 RQD, P/E N/A, ROIC —, cap $1.13B) and TRUP (Trupanion Inc.) posts a C grade (63/100 RQD, P/E 68.2x, ROIC 3.1%, cap $1.32B). Among the 5-stock peer group, TRUP leads on earnings multiple (68.2x) while ALHC leads on capital efficiency (13.9% ROIC).

✓ Pre-computed one-to-many AI Quant brief
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for CSTL?
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Per CSTL's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001447362), Castle Biosciences Inc. generated $344.2M in revenue (+3.7% YoY), -$24.2M in net income, and $28.3M in free cash flow against $578.6M in total assets and $9.6M in total debt. Key quantitative strengths: Big institutional funds and options desks are actively positioning on the bullish side.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief
🤖 AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists — not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).
INTERACTIVE SCENARIO DECK:
🛡️ Portfolio Crash X-Ray
EXT / AFTER-HRS: $38.78 (+0.71%)🧬 Disciplined Float (+0.16% YoY Shares)⚙️ Cash Engine: 13/20 (C) • 8.2% FCF Margin
Verify 90D Bucket Audit →
📊 Historical Track Record: Scores of 63/100 (C) historically posted market-perform odds over rolling 90-day windows (+0.9% avg 90D alpha vs SPY • 54.8% hit rate — wait for RQD ≥ 70 breakout).
Audit Bucket Track Record →
RQD QUANT TACHOMETERHOLD / WATCH • C
025507510063
JEV AI Jury Split (Battleground)
Cash
SEC
Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw C- · Rk C+
Cash (13)Whales (16)SEC (14)Macro (13)CEO (7)
Each axis scored 0–20
12M PRICE TARGET CONE+2.3% Base Target
$46 Bull$39 Base$31 Bear
📬 FREE CSTL RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for CSTL)Realized 20D OHLCV Swing Band: ±11.2%
Deterministic 5-Pillar Attribution (63/100 Composite)
🔍 WHY CSTL SCORES 63/100 (C) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
▲ #1 Bullish Driver: Whale & Options Positioning+16/20 pts (25% of score)

20D Institutional Volume Accumulation (±11.2% realized swing band)

▲ #2 Bullish Driver: SEC 10-K Forensic Risk+14/20 pts (22% of score)

Altman Z-Score 6.97 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 6/9

▼ #1 Drag / Risk Factor: Insider Conviction & Share Dilution7/20 pts (-13 pt drag)

Disciplined Float (+0.16% YoY Shares) & executive Form 4 sales trim 13 pts from alignment

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current
Q1 (-3Q)
55
Grade C$32.76-1.8% Next Q
Q2 (-2Q)
58
Grade C$32.17+3.5% Next Q
Q3 (-1Q)
60
Grade C$33.30+15.6% Next Q
Current
63
Grade C$38.51+0.9% Hist 90D α
Trajectory: C (55) → C (63)Full Audit →
⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)GIDEON ASHMERE // FORENSIC SHORT & KILL-SWITCH DOSSIER

⚔️ Adversarial Opposing Case: Why the CSTL Bull Thesis Could Fail

Gideon Ashmere Forensic Desk →

Even with a 63/100 (C) score, CSTL faces multiple-compression risk if current valuation multiples re-rate toward historical sector medians or if hyperscaler/enterprise customer concentration slows in upcoming 10-Q filings.

⚠️ Forensic Kill-Switch #1

Company executives have done more routine share selling than personal cash buying lately.

⚠️ Forensic Kill-Switch #2

Dilution & Margin Drag: Disciplined Float (+0.16% YoY Shares) — any gross margin slip below 76.9% triggers an automatic RQD downgrade.

⚠️ Forensic Kill-Switch #3

Technical & Forensic Kill-Switch: A daily close below the 50D SMA ($34.30) or 200D SMA ($28.52) invalidates the momentum regime and cuts Target Base ($39.38) toward Bear Floor ($30.72).

🎲 LIVE PREDICTION MARKET ODDS TIED TO $CSTL• $2.4M Crowd Pool • Kalshi / Polymarket Composite
Contract: “CSTL Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”
RSI-14 MOMENTUMBULLISH MOMENTUM
64.630 Oversold · 70 Hot
ALTMAN-Z SHIELDFORTRESS SAFE (>3.0)
6.97>3.0 Fortress Safe
PIOTROSKI F-SCORESOLID CORE (5–6)
6 / 99-Pt Accounting
52-WEEK LASER RANGE78% OF RANGE
L: $18$38.51H: $44
1. Money & Cash Health● MIXED
Are profits real cash in the bank?

Decent core business (79% profit margin), though cash flow growth is moderate rather than explosive right now.

Factor Grade: CRQD 13 / 20
2. Big Money & Insiders● NEUTRAL
Are whales & executives buying or selling?

Big funds and company insiders are mostly holding steady without aggressive buying or panic selling.

Factor Grade: D+RQD 23 / 40
3. Hidden Risks & Market Weather● WATCH
SEC fine-print scan & interest-rate fit

No major SEC filing blowups, though current interest rates and Fed liquidity call for normal position sizing.

Factor Grade: C+RQD 27 / 40
MULTI-MODEL JEV QUANT JURY DELIBERATION

JEV AI Jury Split (Battleground) on CSTL

Cash & Moat Bull AI
ROIC & Free Cash Flow Model
NEUTRAL (65)

-9.3% ROIC with 79.4% gross margin and 2.41% FCF yield.

SEC Forensic Auditor AI
10-K Accruals & Altman-Z Guard
BULLISH (70)

Altman-Z 6.97 and Piotroski 6/9 pass balance-sheet audit.

Whale & Macro Hawk AI
Options Skew, 13F & Fed NetLiq
NEUTRAL (60)

23/40 institutional & smart-money positioning score with 13/20 macro alignment.

Bull Case: Why Buyers Like CSTL
  • ✓Big institutional funds and options desks are actively positioning on the bullish side.
Bear Case: What Could Go Wrong
  • !Company executives have done more routine share selling than personal cash buying lately.
ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Quantitative Research Desk

Scheduled RQD Strong Buys & Whale Accumulation Briefing (CSTL Tape Review)

  • ✓Breakdown of the highest-scoring RQD Green-Light breakouts across our 5,200+ rated universe
  • ✓Forensic Red-Light accounting & dilution traps to review on your watchlist
  • ✓Includes downloadable .ics calendar invite & nightly RQD rating-change email alerts
RQD INSIDER CLUB WAITLIST$49/YR PLANNED
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CSTL // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: +50.90%⚡ TESTING RESISTANCE
2026-11-02O $36.68H $38.51L $36.68C $38.51VOL 723.9K
RES: $39.82SUP: $32.36SMA50: $34.30SMA200: $28.52
$40.19$34.10$28.01$21.92$15.83RES $39.82SUP $32.36$38.512026-05-042026-06-172026-08-042026-09-172026-11-02
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

CSTL Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)
8.0%/yr Implied 5Y Growth

vs. +3.7% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on CSTL today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for CSTL. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for CSTL today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (CSTL)

Health Care Rank #152 of 1016 ⚔️ LMRI vs CSTL Full Matrix →

1. Head-to-Head Health Care Peer Comparison (CSTL vs. LMRI, TRUP, FRNM, ALHC)

Industry: Medical Specialities (41 Tracked Issuers)

Across 1016 tracked Health Care securities in the Roarable RQD universe, Castle Biosciences Inc. (CSTL) ranks #152 by composite RQD confidence (63/100, grade C) and #339 by equity capitalization ($1.18B). Within this direct 5-issuer industry benchmark cohort, TRUP leads on earnings valuation at 68.2x trailing P/E, while ALHC leads on capital efficiency and profitability with 13.9% ROIC and — gross margin. CSTL currently leads its immediate peer cohort in composite quantitative strength at 63/100 (C).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
CSTL ACTIVE
Castle Biosciences Inc.
C 63/100 — 79.4% -9.3% +4.99% $1.18B Benchmark Subject
LMRI
Lumexa Imaging Holdings Inc.
D+ 54/100 — — — +0.95% $1.13B /lmri-vs-cstl →
TRUP
Trupanion Inc.
C 63/100 68.2x 16.1% 3.1% +2.27% $1.32B /trup-vs-cstl →
FRNM
Freenome Inc.
D- 36/100 — — -3.4% -4.32% $1.38B /frnm-vs-cstl →
ALHC
Alignment Healthcare Inc.
D+ 56/100 — — 13.9% -1.47% $1.67B /alhc-vs-cstl →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001447362

In its most recent audited fiscal period (FY2025, filed 2025-12-31), Castle Biosciences Inc. (CSTL) reported GAAP revenue of $344.2M (+3.7% vs. FY2024 revenue of $332.1M , and +56.6% cumulative change since FY2023) , GAAP net income of -$24.2M, operating cash flow of $64.3M, and free cash flow of $28.3M (-22.5% YoY). On the balance sheet, CSTL closed FY2025 with $578.6M in total assets against $9.6M in total debt (Altman Z-Score: 6.97, Piotroski F-Score: 6/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $344.2M -$24.2M $64.3M $28.3M $578.6M $9.6M
FY2024 (FY) 2024-12-31 $332.1M $18.2M $64.9M $36.5M $531.2M $9.7M
FY2023 (FY) 2023-12-31 $219.8M -$57.5M -$5.6M -$5.6M — —

3. CSTL Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is CSTL stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-02, Castle Biosciences Inc. (NASDAQ: CSTL) is rated C (Hold / HOLD) by Roarable's 5-pillar RQD engine with a composite confidence score of 63/100 at a spot price of $38.51 (+4.99% 1D, market cap $1.18B). Pillar breakdown: Fundamental Cash Engine 13/20, Institutional 13F & Options Flow 16/20, Executive Insider Alignment 14/20, FRED Macro Regime Fit 13/20, and SEC Balance-Sheet Forensics 7/20. Across 1016 tracked Health Care issuers, CSTL ranks #152 in composite RQD confidence.

How does CSTL compare to LMRI and TRUP in the Health Care sector?

Within the Health Care sector (Medical Specialities), CSTL carries a Roarable C (63/100 RQD), trailing P/E of N/A, gross margin of 79.4%, and ROIC of -9.3%. By comparison, LMRI (Lumexa Imaging Holdings Inc.) holds a D+ grade (54/100 RQD, P/E N/A, ROIC —, cap $1.13B) and TRUP (Trupanion Inc.) posts a C grade (63/100 RQD, P/E 68.2x, ROIC 3.1%, cap $1.32B). Among the 5-stock peer group, TRUP leads on earnings multiple (68.2x) while ALHC leads on capital efficiency (13.9% ROIC).

What are the biggest fundamental strengths and SEC risk factors for CSTL?

Per CSTL's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001447362), Castle Biosciences Inc. generated $344.2M in revenue (+3.7% YoY), -$24.2M in net income, and $28.3M in free cash flow against $578.6M in total assets and $9.6M in total debt. Key quantitative strengths: Big institutional funds and options desks are actively positioning on the bullish side.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

Where is CSTL trading relative to its 50-day, 200-day, and 52-week technical levels?

CSTL last traded at $38.51 (+4.99% on volume of 723,935 shares), positioning the stock +12.27% above its 50-day simple moving average ($34.30) and +35.03% above its 200-day simple moving average ($28.52). Across its 52-week range of $17.72 to $44.28, CSTL sits at the 78.3% percentile with a 14-day RSI of 64.6 (BULLISH MOMENTUM) and an implied next-earnings move of ±11.2% ($34.20 to $42.82).

CSTL Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS • SEC EDGAR × CBOE × FRED

Should I buy, hold, or sell CSTL stock right now?

Castle Biosciences Inc. (CSTL) currently earns a Roarable Rating of C (Hold — HOLD) with 63/100 RQD Confidence. Solid 79% profit margin (-9% return on capital), mixed timing at current multiples—hold if owned, no rush to chase.

What is CSTL's 12-month price target and RQD AI Jury consensus?

CSTL's 12-month base price target is $39.38 (range $30.72 to $46.49), backed by transparent SEC XBRL cash-flow, Form 4 insider, and CBOE options flow analysis.

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