MARKET WIREReuters • 1h ago
Iranians have left Doha talks, draft proposal for US deal being circulated, official says - ReutersIranians have left Doha talks, draft proposal for US deal being circulated, official says Reuters
Why TLPH Stock dropped -3.74% Today — RQD Quant Desk Flash
$1.03 -3.74% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot)
EXT / AFTER-HRS: $1.02
Talphera Inc. (TLPH) carries a Roarable Rating of D- (Sell) with 42/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
ROARABLE D- • SELL / AVOID
Cap $55.5M
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🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is TLPH stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-02, Talphera Inc. (NASDAQ: TLPH) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 42/100 at a spot price of $1.03 (-3.74% 1D, market cap $55.5M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 9/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 12/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, TLPH ranks #482 in composite RQD confidence.
✓ Pre-computed one-to-many AI Quant brief
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does TLPH compare to CLNN and HRTX in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), TLPH carries a Roarable D- (42/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, CLNN (Clene Inc.) holds a E grade (34/100 RQD, P/E N/A, ROIC -35.0%, cap $55.4M) and HRTX (Heron Therapeutics Inc.) posts a D- grade (37/100 RQD, P/E N/A, ROIC -35.0%, cap $55.9M). Among the 5-stock peer group, TLPH leads on earnings multiple (N/A) while TLPH leads on capital efficiency (-35.0% ROIC).
✓ Pre-computed one-to-many AI Quant brief
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for TLPH?
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Per TLPH's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001427925), Talphera Inc. generated $0 in revenue, -$14.3M in net income, and -$11.4M in free cash flow against $29.7M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
✓ Pre-computed one-to-many AI Quant brief
🤖 AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists — not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).
INTERACTIVE SCENARIO DECK:
EXT / AFTER-HRS: $1.02 (-0.86%)🧬 Dilution Drag (+2.48% YoY Shares)⚙️ Cash Engine: 8/20 (D-) • 0% FCF Margin
Verify 90D Bucket Audit →📊 Historical Track Record Warning: Scores below 50 (42/100 · D-) historically underperformed SPY in 71% of rolling 90-day windows (-7.0% avg 90D alpha vs SPY • 29.0% hit rate).
Audit Bucket Track Record →RQD QUANT TACHOMETERSELL / AVOID • D-
3-of-3 JEV AI Jury Bearish Warning
Cash
SEC
Whale
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
5-PILLAR SNOWFLAKE RADARRw E · Rk D+
Each axis scored 0–20
12M PRICE TARGET CONE-6.8% Base Target
WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for TLPH)Realized 20D OHLCV Swing Band: ±8.7%
Deterministic 5-Pillar Attribution (42/100 Composite)
🔍 WHY TLPH SCORES 42/100 (D-) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
▲ #1 Bullish Driver: Macro Regime Fit+12/20 pts (29% of score)
FRED Regime × Technicals: 39% of 52W Range • RSI-14 at 34.6 (NEUTRAL RANGE)
▲ #2 Bullish Driver: SEC 10-K Forensic Risk+10/20 pts (24% of score)
Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 2/9
▼ #1 Drag / Risk Factor: Insider Conviction & Share Dilution4/20 pts (-16 pt drag)
Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment
📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current
Q1 (-3Q)Grade C-$1.08+0% Next Q
50
Q2 (-2Q)Grade D$1.08+0% Next Q
47
Q3 (-1Q)Grade D$1.08-4.6% Next Q
45
CurrentGrade D-$1.03-7% Hist 90D α
42
Trajectory: C- (50) → D- (42)Full Audit →
⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER
⚔️ Adversarial Opposing Case: What Could Spark a TLPH Turnaround Squeeze
While TLPH currently carries a cautious 42/100 (D-) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
🚀 Contrarian Squeeze Trigger #1
Established market leader in Health Care with deep daily trading liquidity.
🚀 Contrarian Squeeze Trigger #2
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($1.15) and Max Pain ($1.08) forces dealer call-delta covering toward $1.65.
🚀 Contrarian Squeeze Trigger #3
Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
🎲 LIVE PREDICTION MARKET ODDS TIED TO $TLPH• $2.4M Crowd Pool • Kalshi / Polymarket Composite
Contract: “TLPH Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”
AUTOMATED RQD QUANT DESK MOVER BRIEFINGFull Market News Desk →
Why TLPH Stock dropped -3.74% Today — RQD Quant Desk Flash
Talphera Inc. (TLPH) dropped -3.74% to $1.03, trading at 39% of its 52-week range ($0.69 – $1.57). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 39% of its 52-week range ($0.69 – $1.57) with RSI-14 at 34.6 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±8.7% around $1.03 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable D- (Sell) backed by 52% gross margin and $0 annual free cash flow.
Live TLPH Headlines & Catalysts
MARKET WIREReuters • 2h ago
China's foreign minister pushes for dialogue to resolve Middle East conflict - ReutersChina's foreign minister pushes for dialogue to resolve Middle East conflict Reuters
MARKET WIREReuters • 3h ago
COMMENTARY: Asia's crude oil imports back to pre-war levels but refined fuels lag - ReutersCOMMENTARY: Asia's crude oil imports back to pre-war levels but refined fuels lag Reuters
MARKET WIREReuters • 4h ago
Saudi civil defence sounds all-clear after alerts in southern cities - ReutersSaudi civil defence sounds all-clear after alerts in southern cities Reuters
MARKET WIREReuters • 5h ago
World's energy supply buffers have been eroded, ADNOC CEO says - ReutersWorld's energy supply buffers have been eroded, ADNOC CEO says Reuters
MARKET WIREReuters • 6h ago
Gold rebounds from one-year low as oil slides ahead of US midterms - ReutersGold rebounds from one-year low as oil slides ahead of US midterms Reuters
MARKET WIREReuters • 7h ago
China's Xi says Middle East should not become battleground for great power rivalry - ReutersChina's Xi says Middle East should not become battleground for great power rivalry Reuters
MARKET WIREReuters • 9h ago
Reliance earnings, lower oil prices power India's Sensex to near two-month high - ReutersReliance earnings, lower oil prices power India's Sensex to near two-month high Reuters
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Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring TLPH)
- ✓Walkthrough of TLPH's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
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TLPH // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: +13.19%⚡ TESTING RESISTANCE
2026-10-30O $1.07H $1.08L $1.03C $1.03VOL 82.5K
RES: $1.09SUP: $1.00SMA50: $1.15SMA200: $1.01
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK
TLPH Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Share Count & Dilution Monitor (#25)
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
Reverse-DCF Expectations Hurdle (#30)
8.0%/yr Implied 5Y Growth
vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
Ellis Vennor Setup Ledger (#33)
No active Ellis Vennor swing setup published on TLPH today. View full Setup Ledger →
🦋 Documented & Second-Order Butterfly Connections
Open Graph →
No direct multi-tier Butterfly edges indexed yet for TLPH. Explore sector supply chains on /butterfly.
AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for TLPH today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (TLPH)
Health Care Rank #482 of 1016
⚔️ CLNN vs TLPH Full Matrix →
1. Head-to-Head Health Care Peer Comparison (TLPH vs. CLNN, HRTX, ONCY, HYPD)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1016 tracked Health Care securities in the Roarable RQD universe, Talphera Inc. (TLPH) ranks #482 by composite RQD confidence (42/100, grade D-) and #734 by equity capitalization ($55.5M). Within this direct 5-issuer industry benchmark cohort, TLPH leads on earnings valuation at N/A trailing P/E, while TLPH leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. HYPD currently holds the highest overall quantitative score in the immediate peer group at 50/100 (D) compared with TLPH at 42/100 (D-).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| TLPH
ACTIVE
Talphera Inc. | D- | 42/100 | — | — | -35.0% | -3.74% | $55.5M | Benchmark Subject |
| CLNN Clene Inc. | E | 34/100 | — | 78.5% | -35.0% | -1.79% | $55.4M | /clnn-vs-tlph → |
| HRTX Heron Therapeutics Inc. | D- | 37/100 | — | 73.3% | -35.0% | -5.67% | $55.9M | /hrtx-vs-tlph → |
| ONCY Oncolytics Biotech Inc. | D | 45/100 | — | — | -35.0% | -0.54% | $56.1M | /oncy-vs-tlph → |
| HYPD Hyperion DeFi Inc. | D | 50/100 | — | 62.7% | -35.0% | -8.13% | $54.1M | /hypd-vs-tlph → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001427925In its most recent audited fiscal period (FY2025, filed 2025-12-31), Talphera Inc. (TLPH) reported GAAP revenue of $0 (N/A vs. FY2024 revenue of $0 ) , GAAP net income of -$14.3M, operating cash flow of -$11.4M, and free cash flow of -$11.4M (+10.4% YoY). On the balance sheet, TLPH closed FY2025 with $29.7M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 2/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $0 | -$14.3M | -$11.4M | -$11.4M | $29.7M | — |
| FY2024 (FY) | 2024-12-31 | $0 | -$13.0M | -$12.7M | -$12.7M | $18.2M | — |
| FY2023 (FY) | 2023-12-31 | $0 | -$18.4M | -$17.5M | -$17.5M | — | — |
3. TLPH Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs TLPH stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-02, Talphera Inc. (NASDAQ: TLPH) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 42/100 at a spot price of $1.03 (-3.74% 1D, market cap $55.5M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 9/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 12/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, TLPH ranks #482 in composite RQD confidence.
How does TLPH compare to CLNN and HRTX in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), TLPH carries a Roarable D- (42/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, CLNN (Clene Inc.) holds a E grade (34/100 RQD, P/E N/A, ROIC -35.0%, cap $55.4M) and HRTX (Heron Therapeutics Inc.) posts a D- grade (37/100 RQD, P/E N/A, ROIC -35.0%, cap $55.9M). Among the 5-stock peer group, TLPH leads on earnings multiple (N/A) while TLPH leads on capital efficiency (-35.0% ROIC).
What are the biggest fundamental strengths and SEC risk factors for TLPH?
Per TLPH's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001427925), Talphera Inc. generated $0 in revenue, -$14.3M in net income, and -$11.4M in free cash flow against $29.7M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Where is TLPH trading relative to its 50-day, 200-day, and 52-week technical levels?
TLPH last traded at $1.03 (-3.74% on volume of 83,509 shares), positioning the stock -10.43% below its 50-day simple moving average ($1.15) and +1.98% above its 200-day simple moving average ($1.01). Across its 52-week range of $0.69 to $1.57, TLPH sits at the 38.6% percentile with a 14-day RSI of 34.6 (NEUTRAL RANGE) and an implied next-earnings move of ±8.7% ($1.00 to $1.12).
TLPH Investor FAQ & Complete 8-Part Research Index
100% OPEN ACCESS • SEC EDGAR × CBOE × FREDWhy is TLPH stock moving today?
Why TLPH Stock dropped -3.74% Today — RQD Quant Desk Flash. Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.