Spyre Therapeutics Inc. (SYRE) β€” RQD Stock Rating Cockpit

$98.96 -0.79% NASDAQ β€’ Public Delayed / 60s Snapshot

Spyre Therapeutics Inc. (SYRE) carries a Roarable Rating of D+ (Sell) with 57/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh money.

ROARABLE D+ β€’ SELL / AVOID Cap $10.33B
INTERACTIVE SCENARIO DECK:
RQD QUANT TACHOMETERSELL / AVOID β€’ D+
025507510057
2-of-3 JEV AI Jury Bearish Warning
Cash
SEC
Whale
5-PILLAR SNOWFLAKE RADARRw D Β· Rk B
Cash (5)Whales (10)SEC (8)Macro (14)CEO (12)
Each axis scored 0–20
12M PRICE TARGET CONE-0.5% Base Target
$116 Bull$99 Base$77 Bear
πŸ”΄ SUNDAY NIGHT PREP β€’ 7:00 PM ET
WHALE OPTIONS TUG-OF-WAR:52% Call Buyers ($2.3M)
48% PutsMax Pain: $97.00
RSI-14 MOMENTUMBULLISH MOMENTUM
59.130 Oversold Β· 70 Hot
ALTMAN-Z SHIELDFORTRESS SAFE (>3.0)
26.00>3.0 Fortress Safe
PIOTROSKI F-SCORESOLID CORE (5–6)
5 / 99-Pt Accounting
52-WEEK LASER RANGE87% OF RANGE
L: $21$98.96H: $110
1. Money & Cash Health● RED FLAG
Are profits real cash in the bank?

Weak cash conversion or heavy valuation strain compared to actual cash earned.

Factor Grade: ERQD 5 / 20
2. Big Money & Insiders● NEUTRAL
Are whales & executives buying or selling?

Big funds and company insiders are mostly holding steady without aggressive buying or panic selling.

Factor Grade: C-RQD 22 / 40
3. Hidden Risks & Market Weather● ALL CLEAR
SEC fine-print scan & interest-rate fit

Clean SEC fine-print check with low hidden accounting risk and favorable interest-rate weather.

Factor Grade: BRQD 30 / 40
MULTI-MODEL JEV QUANT JURY DELIBERATION

2-of-3 JEV AI Jury Bearish Warning on SYRE

Cash & Moat Bull AI
ROIC & Free Cash Flow Model
BEARISH (25)

-20.0% ROIC with 44.0% gross margin and -1.64% FCF yield.

SEC Forensic Auditor AI
10-K Accruals & Altman-Z Guard
BEARISH (36)

Flagged cash-conversion divergence or elevated filing risk disclosures.

Whale & Macro Hawk AI
Options Skew, 13F & Fed NetLiq
NEUTRAL (60)

Put/Call 0.93x with 22/40 institutional & insider flow.

Bull Case: Why Buyers Like SYRE
  • βœ“Clean SEC annual filing review with no major hidden accounting time-bombs.
Bear Case: What Could Go Wrong
  • !Broader market pullbacks can still drag down strong stocks in the short run.
πŸ”΄ SUNDAY NIGHT PREP β€’ 7:00 PM ETHosted Live by Perry Belcher & Guest Forensic Quant Desk

Red-Light Warning Desk: How Pros Profit When Overhyped Stocks Crack (Featuring SYRE)

  • βœ“Live walkthrough of SYRE's RQD Radar, SEC cash-conversion gap & downside levels
  • βœ“3 asymmetric Bear/Hedge setups institutions use when 10-year yields stay elevated
  • βœ“Includes instant 24/7 email alert whenever any of your stocks flip to Red
RQD INSIDER CLUB UPGRADE$49/YEAR
Want Plain-English AI Custom Indicators, Daily Pro Trader Video Clips & SMS Crash Alerts?
SYRE // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: +29.70%πŸ“ HORIZONTAL RANGE
2026-10-30O $96.78H $98.96L $94.68C $96.56VOL 661.1K
RES: $120.5SUP: $70.80SMA50: $90.06SMA200: $73.22
$115.7$92.75$69.78$46.80$23.83RES $120.5SUP $70.80$96.562026-04-302026-06-152026-07-312026-09-162026-10-30
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

SYRE Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)
15.7%/yr Implied 5Y Growth

vs. +17.6% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on SYRE today. View full Setup Ledger β†’

πŸ¦‹ Documented & Second-Order Butterfly Connections Open Graph β†’

No direct multi-tier Butterfly edges indexed yet for SYRE. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for SYRE today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk β†’

SYRE Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS β€’ SEC EDGAR Γ— CBOE Γ— FRED

Should I buy, hold, or sell SYRE stock right now?

Spyre Therapeutics Inc. (SYRE) currently earns a Roarable Rating of D+ (Sell β€” SELL) with 57/100 RQD Confidence. Stretched risk/reward at current multiples (-20% return on capital) under elevated 10-year interest-rate pressure.

What is SYRE's 12-month price target and RQD AI Jury consensus?

SYRE's 12-month base price target is $98.51 (range $76.84 to $116.24), backed by transparent SEC XBRL cash-flow, Form 4 insider, and CBOE options flow analysis.