Stock Ratings / Health Care / PLRX / options

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Pliant Therapeutics Inc. (PLRX) Options Positioning, Max Pain & Unusual Sweeps

$0.86 -0.13% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $0.86

Pliant Therapeutics Inc. (PLRX) carries a Roarable Rating of D (Sell) with 44/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

📊 Historical Track Record Warning: Scores below 50 (44/100 · D) historically underperformed SPY in 71% of rolling 90-day windows →

ROARABLE D • SELL / AVOID Cap $53.3M

📤 Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card

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🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is PLRX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

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As of 2026-11-02, Pliant Therapeutics Inc. (NASDAQ: PLRX) is rated D (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 44/100 at a spot price of $0.86 (-0.13% 1D, market cap $53.3M). Pillar breakdown: Fundamental Cash Engine 7/20, Institutional 13F & Options Flow 12/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 10/20, and SEC Balance-Sheet Forensics 5/20. Across 1016 tracked Health Care issuers, PLRX ranks #446 in composite RQD confidence.

✓ Pre-computed one-to-many AI Quant brief

🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does PLRX compare to HOWL and CNTB in the Health Care sector?

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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), PLRX carries a Roarable D (44/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, HOWL (Werewolf Therapeutics Inc.) holds a D grade (47/100 RQD, P/E N/A, ROIC -35.0%, cap $53.5M) and CNTB (Connect Biopharma Holdings Limited) posts a D- grade (35/100 RQD, P/E N/A, ROIC -35.0%, cap $52.6M). Among the 5-stock peer group, PLRX leads on earnings multiple (N/A) while PLRX leads on capital efficiency (-35.0% ROIC).

✓ Pre-computed one-to-many AI Quant brief

🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for PLRX?

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Per PLRX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001746473), Pliant Therapeutics Inc. generated $0 in revenue, $149.3M in net income, and -$128.7M in free cash flow against $225.2M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief

🤖 AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists — not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).

INTERACTIVE SCENARIO DECK:

🛡️ Portfolio Crash X-Ray

EXT / AFTER-HRS: $0.86 (-0.21%)🧬 Disciplined Float (+0.72% YoY Shares)⚙️ Cash Engine: 7/20 (D-) • 0% FCF Margin

Verify 90D Bucket Audit →

📊 Historical Track Record Warning: Scores below 50 (44/100 · D) historically underperformed SPY in 71% of rolling 90-day windows (-6.5% avg 90D alpha vs SPY • 29.0% hit rate).

Audit Bucket Track Record →

RQD QUANT TACHOMETERSELL / AVOID • D

3-of-3 JEV AI Jury Bearish Warning

Cash

SEC

Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw D- · Rk D

Each axis scored 0–20

12M PRICE TARGET CONE-5.8% Base Target

WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for PLRX)Realized 20D OHLCV Swing Band: ±12.3%

Deterministic 5-Pillar Attribution (44/100 Composite)

🔍 WHY PLRX SCORES 44/100 (D) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag

▲ #1 Bullish Driver: Whale & Options Positioning+12/20 pts (27% of score)

20D Institutional Volume Accumulation (±12.3% realized swing band)

▲ #2 Bullish Driver: SEC 10-K Forensic Risk+10/20 pts (23% of score)

Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 2/9

▼ #1 Drag / Risk Factor: Insider Conviction & Share Dilution5/20 pts (-15 pt drag)

Disciplined Float (+0.72% YoY Shares) & executive Form 4 sales trim 15 pts from alignment

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current

Q1 (-3Q)

Grade C-$1.02-11.8% Next Q

Q2 (-2Q)

Grade D$0.90-4.4% Next Q

Q3 (-1Q)

Grade D$0.86+0% Next Q

Current

Grade D$0.86-6.5% Hist 90D α

Trajectory: C- (52) → D (44)Full Audit →

⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

⚔️ Adversarial Opposing Case: What Could Spark a PLRX Turnaround Squeeze

Gideon Ashmere Forensic Desk →

While PLRX currently carries a cautious 44/100 (D) rating due to Insider Conviction & Share Dilution (5/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

🚀 Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

🚀 Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($1.04) and Max Pain ($0.90) forces dealer call-delta covering toward $1.91.

🚀 Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Disciplined Float (+0.72% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $PLRX• $2.4M Crowd Pool • Kalshi / Polymarket Composite

Contract: “PLRX Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”

YES 44%NO 56%Trade / Inspect Odds →

CALL VS. PUT WHALE SHARE

— (No Active Options Snapshot)

Put/Call Ratio: — (No Active Options Snapshot)

MAX-PAIN EXPIRATION MAGNET

— (No Active Options Snapshot)

No active options chain max-pain snapshot on file

HISTORICAL 20D VOLATILITY SWING

±12.3%

Derived from 20D OHLCV bars (No Active Options Snapshot)

Active Strike Call vs. Put Concentration Ladder (PLRX)

— (No Active Options Snapshot) — No unusual CBOE strike concentration anomalies recorded in the current database snapshot for PLRX.

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ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring PLRX)

✓Walkthrough of PLRX's RQD Radar, SEC cash-conversion gap & downside invalidation levels
✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks

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PLRX // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: -29.51%▼ DESCENDING CHANNEL

2026-10-30O $0.86H $0.88L $0.84C $0.86VOL 169.1K

RES: $1.19SUP: $0.81SMA50: $1.04SMA200: $1.16

PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

PLRX Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

🦋 PLRX Butterfly Map → + Track PLRX →

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)

8.0%/yr Implied 5Y Growth

vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on PLRX today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for PLRX. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video

🎬 No recent verified company-specific video clip queued for PLRX today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →

DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (PLRX)

Health Care Rank #446 of 1016 ⚔️ HOWL vs PLRX Full Matrix →

1. Head-to-Head Health Care Peer Comparison (PLRX vs. HOWL, CNTB, HYPD, IBIO)

Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)

Across 1016 tracked Health Care securities in the Roarable RQD universe, Pliant Therapeutics Inc. (PLRX) ranks #446 by composite RQD confidence (44/100, grade D) and #742 by equity capitalization ($53.3M). Within this direct 5-issuer industry benchmark cohort, PLRX leads on earnings valuation at N/A trailing P/E, while PLRX leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. HYPD currently holds the highest overall quantitative score in the immediate peer group at 50/100 (D) compared with PLRX at 44/100 (D).

Ticker / Company	Roarable Grade	RQD Score	Trailing P/E	Gross Margin	ROIC	1D Change	Market Cap	Head-to-Head
PLRX ACTIVE Pliant Therapeutics Inc.	D	44/100	—	—	-35.0%	-0.13%	$53.3M	Benchmark Subject
HOWL Werewolf Therapeutics Inc.	D	47/100	—	—	-35.0%	-10.35%	$53.5M	/howl-vs-plrx →
CNTB Connect Biopharma Holdings Limited	D-	35/100	—	—	-35.0%	-3.97%	$52.6M	/cntb-vs-plrx →
HYPD Hyperion DeFi Inc.	D	50/100	—	62.7%	-35.0%	-8.13%	$54.1M	/hypd-vs-plrx →
IBIO iBio Inc.	E	23/100	—	—	-35.0%	-5.52%	$52.3M	/ibio-vs-plrx →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001746473

In its most recent audited fiscal period (FY2025, filed 2025-12-31), Pliant Therapeutics Inc. (PLRX) reported GAAP revenue of $0 (N/A vs. FY2024 revenue of $0 , and -100.0% cumulative change since FY2023) , GAAP net income of $149.3M, operating cash flow of -$128.3M, and free cash flow of -$128.7M (+19.2% YoY). On the balance sheet, PLRX closed FY2025 with $225.2M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 2/9).

Fiscal Period	Filing Date	Revenue	Net Income	Operating Cash Flow	Free Cash Flow	Total Assets	Total Debt
FY2025 (FY)	2025-12-31	$0	$149.3M	-$128.3M	-$128.7M	$225.2M	—
FY2024 (FY)	2024-12-31	$0	$210.3M	-$155.5M	-$159.4M	$396.9M	—
FY2023 (FY)	2023-12-31	$1.6M	$161.3M	-$116.4M	-$116.4M	—	—

3. PLRX Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is PLRX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

How does PLRX compare to HOWL and CNTB in the Health Care sector?

What are the biggest fundamental strengths and SEC risk factors for PLRX?

Where is PLRX trading relative to its 50-day, 200-day, and 52-week technical levels?

PLRX last traded at $0.86 (-0.13% on volume of 169,528 shares), positioning the stock -17.31% below its 50-day simple moving average ($1.04) and -25.86% below its 200-day simple moving average ($1.16). Across its 52-week range of $0.83 to $1.82, PLRX sits at the 3.0% percentile with a 14-day RSI of 35.3 (NEUTRAL RANGE) and an implied next-earnings move of ±12.3% ($1.00 to $0.97).

PLRX Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS • SEC EDGAR × CBOE × FRED

What is PLRX's options positioning and volatility profile?

Roarable tracks verified CBOE unusual options sweeps, put/call ratios, and OHLCV realized volatility bands for PLRX.

Direct Sub-Reports: PLRX RQD Cockpit PLRX 12M Forecast PLRX Earnings & Move PLRX Dividends & DRIP PLRX Insiders & 13F PLRX Whale Options PLRX Profit Sankey PLRX News & Why