Iran's IRGC Navy says two tankers 'exploded' after hitting mines in Hormuz Reuters
Why NCNA Stock dropped -3.26% Today — RQD Quant Desk Flash
NuCana plc (NCNA) carries a Roarable Rating of D+ (Sell) with 56/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
FRED Regime × Technicals: 3% of 52W Range • RSI-14 at 40.3 (NEUTRAL RANGE)
Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 7/9
Put hedging (50% put share) caps near-term gamma upside (-13 pts vs max)
⚔️ Adversarial Opposing Case: Why the NCNA Bull Thesis Could Fail
Even with a 56/100 (D+) score, NCNA faces multiple-compression risk if current valuation multiples re-rate toward historical sector medians or if hyperscaler/enterprise customer concentration slows in upcoming 10-Q filings.
Company executives have done more routine share selling than personal cash buying lately.
Dilution & Margin Drag: Disciplined Float (-0.40% YoY Shares) — any gross margin slip below 49.5% triggers an automatic RQD downgrade.
Technical & Forensic Kill-Switch: A daily close below the 50D SMA ($1.24) or 200D SMA ($1.75) invalidates the momentum regime and cuts Target Base ($1.03) toward Bear Floor ($0.80).
Why NCNA Stock dropped -3.26% Today — RQD Quant Desk Flash
NuCana plc (NCNA) dropped -3.26% to $1.04, trading at 3% of its 52-week range ($0.95 – $4.55). Stretched risk/reward at current multiples (steady margins) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 3% of its 52-week range ($0.95 – $4.55) with RSI-14 at 40.3 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±12.5% around $1.04 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable D+ (Sell) backed by 52% gross margin and $121197 annual free cash flow.
The market could use a few victories in the days ahead, which will be filled with more earnings, an election, and jobs data.
Haley Stevens had lost the Democratic nomination for Senate in Michigan to Abdul El-Sayed earlier this year.
Israeli strikes kill eight people in Gaza - medics say Reuters
Russia's FSB says minor detained over park attack threat after US tip-off Reuters
Iran, Qatari mediators hold third day of talks to end US-Iran war Reuters
Qatar surges, bucking Gulf market slide on Iran war concerns Reuters
OPEC+ keeps December oil output targets steady ahead of tougher call for 2027 Reuters
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring NCNA)
- ✓Walkthrough of NCNA's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
NCNA Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on NCNA today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for NCNA. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (NCNA)
1. Head-to-Head Health Care Peer Comparison (NCNA vs. XTLB, DRMA, AZTR, MDCX)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1016 tracked Health Care securities in the Roarable RQD universe, NuCana plc (NCNA) ranks #271 by composite RQD confidence (56/100, grade D+) and #956 by equity capitalization ($4.3M). Within this direct 5-issuer industry benchmark cohort, NCNA leads on earnings valuation at N/A trailing P/E, while DRMA leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. NCNA currently leads its immediate peer cohort in composite quantitative strength at 56/100 (D+).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| NCNA
ACTIVE
NuCana plc | D+ | 56/100 | — | — | — | -3.26% | $4.3M | Benchmark Subject |
| XTLB XTL Biopharmaceuticals Ltd. | D | 47/100 | — | — | — | -12.44% | $4.3M | /xtlb-vs-ncna → |
| DRMA Dermata Therapeutics Inc. | D- | 43/100 | — | — | -35.0% | -3.84% | $4.2M | /drma-vs-ncna → |
| AZTR Azitra Inc | D- | 41/100 | — | — | -35.0% | -16.31% | $4.6M | /aztr-vs-ncna → |
| MDCX Medicus Pharma Ltd. | D- | 35/100 | — | — | -35.0% | -13.31% | $4.1M | /mdcx-vs-ncna → |
2. NCNA Fundamental Profitability, Capital Efficiency & Balance-Sheet Forensics
TRAILING 12M & FORWARD QUANTITATIVE SNAPSHOTNuCana plc (NCNA) operates in Biotechnology: Pharmaceutical Preparations (Health Care) with an equity capitalization of $4.3M, trailing P/E of N/A, forward P/E of N/A, and EV/EBITDA of N/A. Operating profitability registers a gross margin of —, operating margin of —, net profit margin of —, ROIC of —, and free cash flow yield of —, alongside an Altman Z-Score of N/A and Piotroski F-Score of N/A.
3. NCNA Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs NCNA stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-01, NuCana plc (NASDAQ: NCNA) is rated D+ (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 56/100 at a spot price of $1.04 (-3.26% 1D, market cap $4.3M). Pillar breakdown: Fundamental Cash Engine 12/20, Institutional 13F & Options Flow 7/20, Executive Insider Alignment 13/20, FRED Macro Regime Fit 15/20, and SEC Balance-Sheet Forensics 9/20. Across 1016 tracked Health Care issuers, NCNA ranks #271 in composite RQD confidence.
How does NCNA compare to XTLB and DRMA in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), NCNA carries a Roarable D+ (56/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of —. By comparison, XTLB (XTL Biopharmaceuticals Ltd.) holds a D grade (47/100 RQD, P/E N/A, ROIC —, cap $4.3M) and DRMA (Dermata Therapeutics Inc.) posts a D- grade (43/100 RQD, P/E N/A, ROIC -35.0%, cap $4.2M). Among the 5-stock peer group, NCNA leads on earnings multiple (N/A) while DRMA leads on capital efficiency (-35.0% ROIC).
What are the biggest fundamental strengths and SEC risk factors for NCNA?
For NuCana plc (NCNA), key quantitative strengths include Established market leader in Health Care with deep daily trading liquidity. and sector rank #271 in Health Care, while primary risk factors center on Company executives have done more routine share selling than personal cash buying lately. and implied 5-year growth hurdle of 8.0%/yr. Institutional options positioning shows a 50% call / 50% put premium split.
Where is NCNA trading relative to its 50-day, 200-day, and 52-week technical levels?
NCNA last traded at $1.04 (-3.26% on volume of 11,691 shares), positioning the stock -16.13% below its 50-day simple moving average ($1.24) and -40.57% below its 200-day simple moving average ($1.75). Across its 52-week range of $0.95 to $4.55, NCNA sits at the 2.5% percentile with a 14-day RSI of 40.3 (NEUTRAL RANGE) and an implied next-earnings move of ±12.5% ($1.00 to $1.17).
NCNA Investor FAQ & Complete 8-Part Research Index
100% OPEN ACCESS • SEC EDGAR × CBOE × FREDWhy is NCNA stock moving today?
Why NCNA Stock dropped -3.26% Today — RQD Quant Desk Flash. Stretched risk/reward at current multiples (steady margins) under elevated 10-year interest-rate pressure.