Neurocrine Biosciences Inc. (NBIX) Revenue-to-Profit Sankey Flow & SEC XBRL Financials

$146.38 +0.58% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot)

Neurocrine Biosciences Inc. (NBIX) earns a Roarable Rating of B (Buy) with 73/100 RQD Confidence. High-quality cash engine (96% profit margin, 16% return on capital) with steady institutional support. The company’s underlying cash engine and institutional positioning keep the composite score in the Green Buy zone.

ROARABLE B • BUY Cap $14.88B
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RQD QUANT TACHOMETERBUY • B
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Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

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VISUAL REVENUE-TO-PROFIT SANKEY WATERFALL • FY 2025 (10-K)

How NBIX Turns Every Dollar of Sales Into Real Bottom-Line Profit

Free Cash Flow:$748.7M (26.2% FCF Margin)
Revenue$2.86BGross Profit $2.81B (98.2%)Cost of Sales $52.1MOp Profit $619.1M (21.6%)OpEx (R&D/SG&A) $2.19BNet Profit$478.6M (16.7%)Tax/Other $140.5M

Multi-Year SEC EDGAR XBRL Revenue, Net Profit & Free Cash Flow Trajectory

■ Revenue■ Net Profit■ Free Cash Flow
FY23
Rev $1.89B
FY24
Rev $2.36B
FY25
Rev $2.86B
Fiscal YearRevenueGross MarginOp MarginNet ProfitFree Cash FlowROIC %
FY 2025$2.86B98.2%21.6%$478.6M$748.7M15.5%
FY 2024$2.36B98.6%24.2%$341.3M$557.2M15.7%
FY 2023$1.89B92%13.3%$249.7M$305.0M4%
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NBIX // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: +9.18%▲ RESISTANCE BREAKOUT
2026-11-01O $145.5H $146.4L $145.5C $146.4VOL 831.6K
RES: $137.5SUP: $126.7SMA50: $146.5SMA200: $147.4
$190.0$173.9$157.7$141.5$125.3RES $137.5SUP $126.7$146.42026-05-042026-06-172026-08-042026-09-172026-11-01
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NBIX Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)
24.0%/yr Implied 5Y Growth

vs. +21.4% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on NBIX today. View full Setup Ledger →

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No direct multi-tier Butterfly edges indexed yet for NBIX. Explore sector supply chains on /butterfly.

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DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (NBIX)

Health Care Rank #44 of 188 ⚔️ HALO vs NBIX Full Matrix →

1. Head-to-Head Health Care Peer Comparison (NBIX vs. HALO, EXEL, TWST, TECH)

Industry: Biotechnology: Biological Products (No Diagnostic Substances) (26 Tracked Issuers)

Across 188 tracked Health Care securities in the Roarable RQD universe, Neurocrine Biosciences Inc. (NBIX) ranks #44 by composite RQD confidence (73/100, grade B) and #81 by equity capitalization ($14.88B). Within this direct 5-issuer industry benchmark cohort, EXEL leads on earnings valuation at 21.0x trailing P/E, while EXEL leads on capital efficiency and profitability with 35.1% ROIC and 96.0% gross margin. EXEL currently holds the highest overall quantitative score in the immediate peer group at 89/100 (A) compared with NBIX at 73/100 (B).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
NBIX ACTIVE
Neurocrine Biosciences Inc.
B 73/100 31.1x 96.0% 15.7% +0.58% $14.88B Benchmark Subject
HALO
Halozyme Therapeutics Inc.
B 75/100 47.0x 83.6% 18.0% +0.88% $14.89B /halo-vs-nbix →
EXEL
Exelixis Inc.
A 89/100 21.0x 96.0% 35.1% -0.12% $16.40B /exel-vs-nbix →
TWST
Twist Bioscience Corporation
D+ 52/100 — 94.2% -11.7% 0.00% $11.50B /twst-vs-nbix →
TECH
Bio-Techne Corp
B 72/100 155.3x 64.8% 3.4% +0.03% $11.40B /tech-vs-nbix →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0000914475

In its most recent audited fiscal period (FY2025, filed 2025-12-31), Neurocrine Biosciences Inc. (NBIX) reported GAAP revenue of $2.86B (+21.4% vs. FY2024 revenue of $2.36B , and +51.6% cumulative change since FY2023) , GAAP net income of $478.6M, operating cash flow of $782.7M, and free cash flow of $748.7M (+34.4% YoY). On the balance sheet, NBIX closed FY2025 with $4.63B in total assets against $620.3M in total debt (Altman Z-Score: 8.13, Piotroski F-Score: 9/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $2.86B $478.6M $782.7M $748.7M $4.63B $620.3M
FY2024 (FY) 2024-12-31 $2.36B $341.3M $595.4M $557.2M $3.72B $508.1M
FY2023 (FY) 2023-12-31 $1.89B $249.7M $389.9M $305.0M $8.18B $1.91B

3. NBIX Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is NBIX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-01, Neurocrine Biosciences Inc. (NASDAQ: NBIX) is rated B (Buy / BUY) by Roarable's 5-pillar RQD engine with a composite confidence score of 73/100 at a spot price of $146.38 (+0.58% 1D, market cap $14.88B). Pillar breakdown: Fundamental Cash Engine 18/20, Institutional 13F & Options Flow 11/20, Executive Insider Alignment 18/20, FRED Macro Regime Fit 11/20, and SEC Balance-Sheet Forensics 15/20. Across 188 tracked Health Care issuers, NBIX ranks #44 in composite RQD confidence.

How does NBIX compare to HALO and EXEL in the Health Care sector?

Within the Health Care sector (Biotechnology: Biological Products (No Diagnostic Substances)), NBIX carries a Roarable B (73/100 RQD), trailing P/E of 31.1x, gross margin of 96.0%, and ROIC of 15.7%. By comparison, HALO (Halozyme Therapeutics Inc.) holds a B grade (75/100 RQD, P/E 47.0x, ROIC 18.0%, cap $14.89B) and EXEL (Exelixis Inc.) posts a A grade (89/100 RQD, P/E 21.0x, ROIC 35.1%, cap $16.40B). Among the 5-stock peer group, EXEL leads on earnings multiple (21.0x) while EXEL leads on capital efficiency (35.1% ROIC).

What are the biggest fundamental strengths and SEC risk factors for NBIX?

Per NBIX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0000914475), Neurocrine Biosciences Inc. generated $2.86B in revenue (+21.4% YoY), $478.6M in net income, and $748.7M in free cash flow against $4.63B in total assets and $620.3M in total debt. Key quantitative strengths: Strong cash generator (96% profit margin)—profits are backed by real money, not accounting tricks.. Primary risk factors monitored: Broader market pullbacks can still drag down strong stocks in the short run.. Institutional options positioning shows a 50% call / 50% put premium split.

Where is NBIX trading relative to its 50-day, 200-day, and 52-week technical levels?

NBIX last traded at $146.38 (+0.58% on volume of 831,620 shares), positioning the stock -0.09% below its 50-day simple moving average ($146.51) and -0.72% below its 200-day simple moving average ($147.44). Across its 52-week range of $122.14 to $186.12, NBIX sits at the 37.9% percentile with a 14-day RSI of 56.1 (BULLISH MOMENTUM) and an implied next-earnings move of ±4.8% ($139.35 to $153.41).

NBIX Investor FAQ & Complete 8-Part Research Index

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How profitable is Neurocrine Biosciences Inc. (NBIX)?

In FY 2025 (10-K), NBIX converted $2.9B of revenue into a 98.2% gross margin, 21.6% operating margin, and $748.7M in free cash flow (26.2% FCF margin).