Yahoo Finance UK report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
Why ANTX Stock dropped -3.41% Today — RQD Quant Desk Flash
AN2 Therapeutics Inc. (ANTX) carries a Roarable Rating of D (Sell) with 46/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is ANTX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-02, AN2 Therapeutics Inc. (NASDAQ: ANTX) is rated D (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 46/100 at a spot price of $4.53 (-3.41% 1D, market cap $177.0M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 13/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 12/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, ANTX ranks #380 in composite RQD confidence.
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does ANTX compare to ADAG and ORMP in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), ANTX carries a Roarable D (46/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, ADAG (Adagene Inc.) holds a E grade (30/100 RQD, P/E N/A, ROIC -35.0%, cap $177.0M) and ORMP (Oramed Pharmaceuticals Inc.) posts a D- grade (41/100 RQD, P/E N/A, ROIC -7.8%, cap $176.0M). Among the 5-stock peer group, ANTX leads on earnings multiple (N/A) while ORMP leads on capital efficiency (-7.8% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for ANTX?
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Per ANTX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001880438), AN2 Therapeutics Inc. generated $0 in revenue, -$35.2M in net income, and -$29.8M in free cash flow against $62.0M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
20D Institutional Volume Accumulation (±12.5% realized swing band)
FRED Regime × Technicals: 57% of 52W Range • RSI-14 at 54 (NEUTRAL RANGE)
Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment
⚔️ Adversarial Opposing Case: What Could Spark a ANTX Turnaround Squeeze
While ANTX currently carries a cautious 46/100 (D) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($4.90) and Max Pain ($4.76) forces dealer call-delta covering toward $7.55.
Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why ANTX Stock dropped -3.41% Today — RQD Quant Desk Flash
AN2 Therapeutics Inc. (ANTX) dropped -3.41% to $4.53, trading at 57% of its 52-week range ($1 – $7.19). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 57% of its 52-week range ($1 – $7.19) with RSI-14 at 54 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±12.5% around $4.53 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable D (Sell) backed by 52% gross margin and $0 annual free cash flow.
TradingView report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
Business Wire report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
Business Wire report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
https://www.siam.in/ report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
MENLO PARK, Calif., November 02, 2026--AN2 Therapeutics, Inc. (Nasdaq: ANTX), a clinical stage biopharmaceutical company focused on the discovery and development of novel small molecule therapeutics derived from its boro
MENLO PARK, Calif., October 21, 2026--AN2 Therapeutics, Inc. (Nasdaq: ANTX), a clinical stage biopharmaceutical company focused on the discovery and development of novel small molecule therapeutics derived from its boron
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring ANTX)
- ✓Walkthrough of ANTX's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
ANTX Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on ANTX today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for ANTX. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (ANTX)
1. Head-to-Head Health Care Peer Comparison (ANTX vs. ADAG, ORMP, UPB, SION)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1016 tracked Health Care securities in the Roarable RQD universe, AN2 Therapeutics Inc. (ANTX) ranks #380 by composite RQD confidence (46/100, grade D) and #595 by equity capitalization ($177.0M). Within this direct 5-issuer industry benchmark cohort, ANTX leads on earnings valuation at N/A trailing P/E, while ORMP leads on capital efficiency and profitability with -7.8% ROIC and 0.7% gross margin. ANTX currently leads its immediate peer cohort in composite quantitative strength at 46/100 (D).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| ANTX
ACTIVE
AN2 Therapeutics Inc. | D | 46/100 | — | — | -35.0% | -3.41% | $177.0M | Benchmark Subject |
| ADAG Adagene Inc. | E | 30/100 | — | — | -35.0% | -6.34% | $177.0M | /adag-vs-antx → |
| ORMP Oramed Pharmaceuticals Inc. | D- | 41/100 | — | 0.7% | -7.8% | -2.84% | $176.0M | /ormp-vs-antx → |
| UPB Upstream Bio Inc. | D- | 42/100 | — | — | -35.0% | +4.28% | $179.1M | /upb-vs-antx → |
| SION Sionna Therapeutics Inc. | D- | 38/100 | — | — | -28.3% | -3.25% | $180.8M | /sion-vs-antx → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001880438In its most recent audited fiscal period (FY2025, filed 2025-12-31), AN2 Therapeutics Inc. (ANTX) reported GAAP revenue of $0 (N/A vs. FY2024 revenue of $0 ) , GAAP net income of -$35.2M, operating cash flow of -$29.8M, and free cash flow of -$29.8M (+39.4% YoY). On the balance sheet, ANTX closed FY2025 with $62.0M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 3/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $0 | -$35.2M | -$29.8M | -$29.8M | $62.0M | — |
| FY2024 (FY) | 2024-12-31 | $0 | -$51.3M | -$49.3M | -$49.3M | $92.1M | — |
| FY2023 (FY) | 2023-12-31 | $0 | -$64.7M | -$53.3M | -$53.3M | — | — |
3. ANTX Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs ANTX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-02, AN2 Therapeutics Inc. (NASDAQ: ANTX) is rated D (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 46/100 at a spot price of $4.53 (-3.41% 1D, market cap $177.0M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 13/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 12/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, ANTX ranks #380 in composite RQD confidence.
How does ANTX compare to ADAG and ORMP in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), ANTX carries a Roarable D (46/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, ADAG (Adagene Inc.) holds a E grade (30/100 RQD, P/E N/A, ROIC -35.0%, cap $177.0M) and ORMP (Oramed Pharmaceuticals Inc.) posts a D- grade (41/100 RQD, P/E N/A, ROIC -7.8%, cap $176.0M). Among the 5-stock peer group, ANTX leads on earnings multiple (N/A) while ORMP leads on capital efficiency (-7.8% ROIC).
What are the biggest fundamental strengths and SEC risk factors for ANTX?
Per ANTX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001880438), AN2 Therapeutics Inc. generated $0 in revenue, -$35.2M in net income, and -$29.8M in free cash flow against $62.0M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Where is ANTX trading relative to its 50-day, 200-day, and 52-week technical levels?
ANTX last traded at $4.53 (-3.41% on volume of 284,726 shares), positioning the stock -7.55% below its 50-day simple moving average ($4.90) and +11.30% above its 200-day simple moving average ($4.07). Across its 52-week range of $1.00 to $7.19, ANTX sits at the 57.0% percentile with a 14-day RSI of 54.0 (NEUTRAL RANGE) and an implied next-earnings move of ±12.5% ($3.96 to $5.10).
ANTX Investor FAQ & Complete 8-Part Research Index
100% OPEN ACCESS • SEC EDGAR × CBOE × FREDWhy is ANTX stock moving today?
Why ANTX Stock dropped -3.41% Today — RQD Quant Desk Flash. Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
ANTX — AN2 Therapeutics Inc.: What the Facts Mean to a Prospective Investor
Roarable Rating Brief: What This Means to a Prospective Investor
Per the Roarable RQD rating, ANTX scores 46 out of 100, a letter grade of D, labeled "Roarable Sell — Underperform / Distribution Warning." The five pillars are: Fundamental Cash Engine at 8/20 (ROIC of -35% and FCF yield of -16.86%), Whale 13F Flow at 13/20 (institutional accumulation and options positioning), Insider Conviction at 3/20 (SEC Form 4 and Congressional PTR cluster flow), Macro Regime Fit at 12/20 (beta 1.0 and sector sensitivity), and Forensic Balance Sheet at 10/20 (Altman Z 2.5, Piotroski F 3/9, Debt/Equity 0.5). Per the same rating, the cash-generation and insider-conviction pillars are the weakest, meaning the business is consuming rather than producing cash and insider activity offers little support. The strongest pillar, institutional flow, is still only moderate. For a prospective investor, the implication is that valuation support must come from future clinical or commercial outcomes rather than current operating economics, which carries elevated risk of further dilution or drawdown if those outcomes slip.
Business
AN2 Therapeutics Inc. is a NASDAQ-listed issuer in the Health Care sector, within the Biotechnology: Pharmaceutical Preparations industry, per the Profile section. The source data does not identify its products, customers, or revenue model. The FY 2023–FY 2025 financials report revenue of $0.0M in each period, per the SEC financials section, so the company is not currently generating reported revenue. Not available in source data for further business detail.
Financial Trend
| Period | Revenue | Operating Income | Net Income | EPS | FCF | Cash | Debt |
|---|---|---|---|---|---|---|---|
| FY 2025 | $0.0M | $-38.1M | $-35.2M | N/A | $-29.8M | $19.9M | N/A |
| FY 2024 | $0.0M | $-56.8M | $-51.3M | N/A | $-49.3M | $21.4M | N/A |
| FY 2023 | $0.0M | $-69.6M | $-64.7M | N/A | $-53.3M | N/A | N/A |
Per the SEC financials, losses narrowed from $-64.7M net income in FY 2023 to $-35.2M in FY 2025, while reported cash declined from $21.4M to $19.9M. Per the market data section, gross, operating, and net margins are each 0%, and ROIC is -35%. Per the Roarable RQD rating, the Altman Z-Score is 2.5 and the Piotroski F-Score is 3/9, with Debt/Equity of 0.5. Per the financials, debt is not reported, so the Debt/Equity figure cannot be reconciled against the reported debt line.
Recent Catalysts & News Wire Analysis
Per the recent news section, six items are dated within roughly the prior 15 hours of the data timestamp. Catalysts include a Yahoo Finance UK and TradingView item covering market action, a Stock Titan item discussing a planned study with clearance in three countries and an estimated 155,000 U.S. patients with the targeted blood cancer, a Business Wire item on inducement grants under Listing Rule 5635(c)(4), a Stock Titan item on a director receiving 2,283 shares instead of cash, and a Business Wire item on upcoming investor conferences. Every item carries a YELLOW light and MARKET WIRE impact label. Risk watch items include the inducement grants and the director share-in-lieu-of-cash arrangement, both of which are routine compensation mechanics but still relate to equity issuance. Per the Butterfly Supply-Chain Graph, no proprietary signals are listed.
Open Questions
- What products or clinical programs generate ANTX's value, and what is the timeline to revenue given reported revenue of $0.0M across three periods?
- What is the reported debt balance, given that debt is listed as N/A for every period while Debt/Equity is cited at 0.5?
- What is the cash runway implied by $19.9M in cash against FY 2025 FCF of $-29.8M, and what financing has been or may be required?
- What are the specific holders, insider transactions, and analyst estimates behind the RQD whale and insider pillar scores?
- What are the terms and dilution impact of the inducement grants and share-in-lieu-of-cash arrangements referenced in recent news?
ANTX Live News Feed, Press Releases & Catalyst Wire
Real-time company headlines, analyst actions, and sector developments for AN2 Therapeutics Inc. (ANTX) • Click "Debate This Headline" to argue it in the Roar Pit below
Yahoo Finance UK report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
TradingView report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
Business Wire report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
Business Wire report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
https://www.siam.in/ report covering AN2 Therapeutics Inc. (ANTX) market action, institutional positioning, and fundamental catalysts.
MENLO PARK, Calif., November 02, 2026--AN2 Therapeutics, Inc. (Nasdaq: ANTX), a clinical stage biopharmaceutical company focused on the discovery and development of novel small molecule therapeutics derived from its boro
ANTX Bull vs. Bear Conversation Board — What's Your Call at $4.53?
🔥 Official Bull vs. Bear Debate: Is ANTX (D • RQD 46/100) a Buy at $4.53?
Welcome to the ANTX (AN2 Therapeutics Inc.) Roar Pit. Current RQD Composite is 46/100 (Roarable Sell — Underperform / Distribution Warning) in Biotechnology: Pharmaceutical Preparations. Bulls point to operating leverage and sector positioning, while bears focus on macro rate sensitivity and margin execution. Pick your side (🐂 Bull or 🐻 Bear) and drop your price target below.
Pump the brakes on ANTX — check the valuation vs. margin headwinds
Everyone in here is repeating the bull case on ANTX, but look at what you are paying: current EV/EBITDA multiples with tightening sector spreads. Unless AN2 Therapeutics Inc. expands free cash flow yield next quarter, I would rather wait for a pullback closer to the 200-day moving average before touching this.
ANTX cash flow & RQD setup is being underpriced by the Street here
Looking at the 5-pillar RQD breakdown on ANTX, the market is fixating on short-term headline noise in Biotechnology: Pharmaceutical Preparations and ignoring the balance sheet and cash flow trajectory. At $4.53 (52-wk range $1.00 - $7.19), any beat on forward guidance forces shorts and underweight funds to chase.