MeiraGTx Holdings plc (MGTX) — RQD Stock Rating Cockpit

$9.71 -0.46% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $9.68

MeiraGTx Holdings plc (MGTX) carries a Roarable Rating of E (Strong Sell) with 21/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

ROARABLE E • RED ALERT Cap $932.1M
📤 Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card
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🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is MGTX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-02, MeiraGTx Holdings plc (NASDAQ: MGTX) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 21/100 at a spot price of $9.71 (-0.46% 1D, market cap $932.1M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 5/20, Executive Insider Alignment 7/20, FRED Macro Regime Fit 3/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, MGTX ranks #982 in composite RQD confidence.

✓ Pre-computed one-to-many AI Quant brief
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does MGTX compare to GLUE and PRME in the Health Care sector?
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Within the Health Care sector (Biotechnology: Biological Products (No Diagnostic Substances)), MGTX carries a Roarable E (21/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, GLUE (Monte Rosa Therapeutics Inc.) holds a E grade (27/100 RQD, P/E N/A, ROIC -35.0%, cap $927.4M) and PRME (Prime Medicine Inc.) posts a E grade (31/100 RQD, P/E N/A, ROIC -35.0%, cap $950.4M). Among the 5-stock peer group, MGTX leads on earnings multiple (N/A) while MGTX leads on capital efficiency (-35.0% ROIC).

✓ Pre-computed one-to-many AI Quant brief
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for MGTX?
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Per MGTX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001735438), MeiraGTx Holdings plc generated $81.4M in revenue (+144.6% YoY), $0 in net income, and -$50.2M in free cash flow against $244.4M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief
🤖 AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists — not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).
INTERACTIVE SCENARIO DECK:
🛡️ Portfolio Crash X-Ray
EXT / AFTER-HRS: $9.68 (-0.27%)🧬 Dilution Drag (+2.48% YoY Shares)⚙️ Cash Engine: 3/20 (E) • 0% FCF Margin
Verify 90D Bucket Audit →
📊 Historical Track Record Warning: Scores below 50 (21/100 · E) historically underperformed SPY in 71% of rolling 90-day windows (-11.6% avg 90D alpha vs SPY • 29.0% hit rate).
Audit Bucket Track Record →
RQD QUANT TACHOMETERRED ALERT • E
025507510021
3-of-3 JEV AI Jury Bearish Warning
Cash
SEC
Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw E · Rk E
Cash (3)Whales (5)SEC (7)Macro (3)CEO (3)
Each axis scored 0–20
12M PRICE TARGET CONE-16.7% Base Target
$16 Bull$8 Base$6 Bear
📬 FREE MGTX RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for MGTX)Realized 20D OHLCV Swing Band: ±10.7%
Deterministic 5-Pillar Attribution (21/100 Composite)
🔍 WHY MGTX SCORES 21/100 (E) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
▲ #1 Bullish Driver: SEC 10-K Forensic Risk+7/20 pts (33% of score)

Altman Z-Score 0.20 (DISTRESS RISK (<1.8)) • Piotroski F-Score 1/9

▲ #2 Bullish Driver: Whale & Options Positioning+5/20 pts (24% of score)

20D Institutional Volume Accumulation (±10.7% realized swing band)

▼ #1 Drag / Risk Factor: Insider Conviction & Share Dilution4/20 pts (-16 pt drag)

Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current
Q1 (-3Q)
29
Grade E$10.38-9% Next Q
Q2 (-2Q)
26
Grade E$9.45-2.9% Next Q
Q3 (-1Q)
24
Grade E$9.18+5.8% Next Q
Current
21
Grade E$9.71-11.6% Hist 90D α
Trajectory: E (29) → E (21)Full Audit →
⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

⚔️ Adversarial Opposing Case: What Could Spark a MGTX Turnaround Squeeze

Gideon Ashmere Forensic Desk →

While MGTX currently carries a cautious 21/100 (E) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

🚀 Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

🚀 Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($11.62) and Max Pain ($10.20) forces dealer call-delta covering toward $16.12.

🚀 Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $MGTX• $2.4M Crowd Pool • Kalshi / Polymarket Composite
Contract: “MGTX Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”
RSI-14 MOMENTUMNEUTRAL RANGE
41.930 Oversold · 70 Hot
ALTMAN-Z SHIELDDISTRESS RISK (<1.8)
0.20>3.0 Fortress Safe
PIOTROSKI F-SCOREWEAK QUALITY (1–4)
1 / 99-Pt Accounting
52-WEEK LASER RANGE35% OF RANGE
L: $7$9.71H: $15
1. Money & Cash Health● WEAK
Are profits real cash in the bank?

Weak cash conversion or heavy valuation strain compared to actual cash earned.

Factor Grade: ERQD 3 / 20
2. Big Money & Insiders● TRIMMING
Are whales & executives buying or selling?

Insiders and big institutional desks have been trimming shares rather than stepping up to buy.

Factor Grade: ERQD 8 / 40
3. Hidden Risks & Market Weather● WARNING
SEC fine-print scan & interest-rate fit

High sensitivity to tight interest rates or new risk warnings added to recent SEC annual filings.

Factor Grade: ERQD 10 / 40
MULTI-MODEL JEV QUANT JURY DELIBERATION

3-of-3 JEV AI Jury Bearish Warning on MGTX

Cash & Moat Bull AI
ROIC & Free Cash Flow Model
BEARISH (15)

-35.0% ROIC with 42.0% gross margin and -5.38% FCF yield.

SEC Forensic Auditor AI
10-K Accruals & Altman-Z Guard
BEARISH (35)

Altman-Z 0.20 and Piotroski 1/9 pass balance-sheet audit.

Whale & Macro Hawk AI
Options Skew, 13F & Fed NetLiq
BEARISH (18)

8/40 institutional & smart-money positioning score with 3/20 macro alignment.

Bull Case: Why Buyers Like MGTX
  • ✓Established market leader in Health Care with deep daily trading liquidity.
Bear Case: What Could Go Wrong
  • !Company executives have done more routine share selling than personal cash buying lately.
  • !Sensitive to high interest rates and tighter Federal Reserve market liquidity.
  • !Recent SEC filings added new risk-factor disclosures that warrant keeping an eye on margins.
ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring MGTX)

  • ✓Walkthrough of MGTX's RQD Radar, SEC cash-conversion gap & downside invalidation levels
  • ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
  • ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
RQD INSIDER CLUB WAITLIST$49/YR PLANNED
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MGTX // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: +0.10%📐 HORIZONTAL RANGE
2026-11-02O $9.75H $9.75L $9.71C $9.71VOL 499.2K
RES: $15.26SUP: $8.86SMA50: $11.62SMA200: $10.32
$15.86$13.76$11.67$9.57$7.48RES $15.26SUP $8.86$9.712026-05-042026-06-172026-08-042026-09-172026-11-02
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

MGTX Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)
8.0%/yr Implied 5Y Growth

vs. +144.6% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on MGTX today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for MGTX. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for MGTX today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (MGTX)

Health Care Rank #982 of 1016 ⚔️ GLUE vs MGTX Full Matrix →

1. Head-to-Head Health Care Peer Comparison (MGTX vs. GLUE, PRME, ODTX, CGEM)

Industry: Biotechnology: Biological Products (No Diagnostic Substances) (156 Tracked Issuers)

Across 1016 tracked Health Care securities in the Roarable RQD universe, MeiraGTx Holdings plc (MGTX) ranks #982 by composite RQD confidence (21/100, grade E) and #370 by equity capitalization ($932.1M). Within this direct 5-issuer industry benchmark cohort, MGTX leads on earnings valuation at N/A trailing P/E, while MGTX leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. ODTX currently holds the highest overall quantitative score in the immediate peer group at 52/100 (D+) compared with MGTX at 21/100 (E).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
MGTX ACTIVE
MeiraGTx Holdings plc
E 21/100 — — -35.0% -0.46% $932.1M Benchmark Subject
GLUE
Monte Rosa Therapeutics Inc.
E 27/100 — — -35.0% +0.18% $927.4M /glue-vs-mgtx →
PRME
Prime Medicine Inc.
E 31/100 — — -35.0% -2.24% $950.4M /prme-vs-mgtx →
ODTX
Odyssey Therapeutics Inc.
D+ 52/100 — — — +1.48% $953.0M /odtx-vs-mgtx →
CGEM
Cullinan Therapeutics Inc.
E 32/100 — — -35.0% -0.71% $994.3M /cgem-vs-mgtx →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001735438

In its most recent audited fiscal period (FY2025, filed 2025-12-31), MeiraGTx Holdings plc (MGTX) reported GAAP revenue of $81.4M (+144.6% vs. FY2024 revenue of $33.3M , and +480.7% cumulative change since FY2023) , GAAP net income of $0, operating cash flow of -$46.4M, and free cash flow of -$50.2M (+54.1% YoY). On the balance sheet, MGTX closed FY2025 with $244.4M in total assets against $0 in total debt (Altman Z-Score: 0.20, Piotroski F-Score: 1/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $81.4M $0 -$46.4M -$50.2M $244.4M —
FY2024 (FY) 2024-12-31 $33.3M $0 -$104.5M -$109.5M $269.8M —
FY2023 (FY) 2023-12-31 $14.0M $0 -$105.4M -$105.4M — —

3. MGTX Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is MGTX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-02, MeiraGTx Holdings plc (NASDAQ: MGTX) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 21/100 at a spot price of $9.71 (-0.46% 1D, market cap $932.1M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 5/20, Executive Insider Alignment 7/20, FRED Macro Regime Fit 3/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, MGTX ranks #982 in composite RQD confidence.

How does MGTX compare to GLUE and PRME in the Health Care sector?

Within the Health Care sector (Biotechnology: Biological Products (No Diagnostic Substances)), MGTX carries a Roarable E (21/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, GLUE (Monte Rosa Therapeutics Inc.) holds a E grade (27/100 RQD, P/E N/A, ROIC -35.0%, cap $927.4M) and PRME (Prime Medicine Inc.) posts a E grade (31/100 RQD, P/E N/A, ROIC -35.0%, cap $950.4M). Among the 5-stock peer group, MGTX leads on earnings multiple (N/A) while MGTX leads on capital efficiency (-35.0% ROIC).

What are the biggest fundamental strengths and SEC risk factors for MGTX?

Per MGTX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001735438), MeiraGTx Holdings plc generated $81.4M in revenue (+144.6% YoY), $0 in net income, and -$50.2M in free cash flow against $244.4M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

Where is MGTX trading relative to its 50-day, 200-day, and 52-week technical levels?

MGTX last traded at $9.71 (-0.46% on volume of 499,196 shares), positioning the stock -16.44% below its 50-day simple moving average ($11.62) and -5.91% below its 200-day simple moving average ($10.32). Across its 52-week range of $6.62 to $15.35, MGTX sits at the 35.4% percentile with a 14-day RSI of 41.9 (NEUTRAL RANGE) and an implied next-earnings move of ±10.7% ($8.67 to $10.75).

MGTX Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS • SEC EDGAR × CBOE × FRED

Should I buy, hold, or sell MGTX stock right now?

MeiraGTx Holdings plc (MGTX) currently earns a Roarable Rating of E (Strong Sell — SELL) with 21/100 RQD Confidence. Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.

What is MGTX's 12-month price target and RQD AI Jury consensus?

MGTX's 12-month base price target is $8.09 (range $6.31 to $16.12), backed by transparent SEC XBRL cash-flow, Form 4 insider, and CBOE options flow analysis.

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